Abstract:
Method of delivering a therapeutic agent includes delivering at least a portion of a medical device within a vasculature. The medical device includes a tubular member having a proximal end and distal end defining a longitudinal axis therebetween, an expandable member proximate the distal end of the tubular member, a tissue engaging member proximate the expandable member, a sheath disposed over the tissue engaging member, and a therapeutic agent disposed on at least the expandable member or the tissue engaging member. The method further includes deploying the tissue engaging member at a select location by displacement of the sheath relative the tissue engaging member, inflating the expandable member to engage the therapeutic agent with a vessel wall, deflating the expandable member, and withdrawing the medical device from the vasculature.
Abstract:
System and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A positioning device maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by ejecting a pressurized medium against the surface of the expandable member.
Abstract:
An agent delivery catheter and method configured to deliver an agent to an inner surface of a patient's body lumen wall by forming a funnel shaped agent containment chamber around at least one portion of the inner surface of the body lumen wall, while minimizing ischemic conditions during the procedure.
Abstract:
An agent delivery catheter and method configured to deliver an agent to an inner surface of a patient's body lumen wall by forming a funnel shaped agent containment chamber around at least one portion of the inner surface of the body lumen wall, while minimizing ischemic conditions during the procedure.