专利检索 ap:("Abdelwahed Chtarto" OR "Liliane Tenenbaum" OR "Marc Levivier" OR "Marc Peschanski" OR "Jacques Brotchi" OR "Thierry Velu") AND inv:"Liliane Tenenbaum" 第 1 页

1.

发明授权
Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization 失效
标题翻译：用于基因治疗或基因免疫的抗生素诱导/抑制遗传构建体

公开(公告)号：US06780639B1

公开(公告)日：2004-08-24

申请号：US09645162

申请日：2000-08-24

申请人： Abdelwahed Chtarto , Liliane Tenenbaum , Marc Levivier , Marc Peschanski , Jacques Brotchi , Thierry Velu

发明人： Abdelwahed Chtarto , Liliane Tenenbaum , Marc Levivier , Marc Peschanski , Jacques Brotchi , Thierry Velu

IPC分类号： C12N1574

CPC分类号： A61K38/185

摘要： The present invention is related to an antibiotic inducible/repressible genetic construct for controlling the transcription of a gene of interes: by a cell. The genetic construct comprises a bi-directional antibiotic controlled activator-responsive promoter/operator sequence which is located between the gene of interest and a cistron encoding a reverse antibiotic controlled transactivator and controls the transcription of the gene of interest and of the cistron.

摘要翻译： 本发明涉及用于控制细胞内基因转录的抗生素诱导/抑制性遗传构建体。遗传构建体包含位于感兴趣的基因和编码反向抗生素控制的反式激活因子的顺反子之间的双向抗生素控制的激活剂 - 应答启动子/操纵子序列，并控制感兴趣的基因和顺反子的转录。