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公开(公告)号：US11097134B2
公开(公告)日：2021-08-24
申请号：US16874019
申请日：2020-05-14
Applicant: Academia Sinica
Inventor： Song-Kun Shyue , Szu-Fu Chen , Chun-Hu Wu , Che-Feng Chang
Abstract: A method for treating a neurological disorder, symptom or disease that is associated with an increase in the brain levels of caveolin-1 (Cav-1) in a subject in need thereof is disclosed. The method comprises administering to the subject in need thereof a composition comprising: (a) a therapeutically effective amount of an antibody specific against the Cav-1 or an antigen-binding fragment thereof; and (b) a pharmaceutically acceptable carrier. Methods for reducing cerebral inflammation, brain tissue damage, brain neuronal death, and improving behavioral outcomes or functional recovery related to a hemorrhagic stroke in a subject in need thereof are also disclosed.
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