专利检索 ap:("Academisch Ziekenhuis Leiden h.o.d.n. LUMC") AND inv:"Annemieke AARTSMA-RUS" 第 1 页

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发明申请
MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE 审中-公开

公开(公告)号：US20160194636A1

公开(公告)日：2016-07-07

申请号：US15047233

申请日：2016-02-18

申请人： Academisch Ziekenhuis Leiden h.o.d.n. LUMC

发明人： Judith Christina Theodora Van DEUTEKOM , Garrit-Jan Boudewijn Van OMMEN , Annemieke AARTSMA-RUS , Johannes Theodorus den DUNNEN

IPC分类号： C12N15/113

CPC分类号： C12N15/113 , A61K38/00 , A61K48/00 , A61K48/0016 , C07H21/02 , C12N15/85 , C12N2310/11 , C12N2310/111 , C12N2310/31 , C12N2310/314 , C12N2310/315 , C12N2310/3181 , C12N2310/321 , C12N2310/3231 , C12N2310/3233 , C12N2310/346 , C12N2320/30 , C12N2320/33 , C12Q1/6883 , G01N33/6887 , C12N2310/3521

摘要： The invention relates to oligonucleotides for inducing skipping of exon 53 of the dystrophin gene. The invention also relates to methods of inducing exon 53 skipping using the oligonucleotides.