公开(公告)号：US07560587B2

公开(公告)日：2009-07-14

申请号：US11004331

申请日：2004-12-04

申请人： Adela Goredema ,  Rina Carlini ,  Christine E. Bedford ,  Marcel P. Breton ,  Eniko Toma

发明人： Adela Goredema ,  Rina Carlini ,  Christine E. Bedford ,  Marcel P. Breton ,  Eniko Toma

IPC分类号： C07C275/14

CPC分类号： C07C275/26 ,  C07C2601/14 ,  C09D11/34

摘要： Disclosed is a bis(urea-urethane) compound of the formula wherein R1 and R1′ each, independently of the other, is an alkyl group, wherein at least one of R1 and R1′ has at least about 6 carbon atoms, R2 and R2′ each, independently of the other, is an alkylene group, wherein at least one of R2 and R2′ has at least about 3 carbon atoms, R3 is an alkylene group having at least about 2 carbon atoms, and R4 and R5 each, independently of the other, is a hydrogen atom or an alkyl group, and wherein R1 and R1′ each contain no more than 2 fully fluorinated carbon atoms.

摘要翻译： 公开了下式的双（脲 - 氨基甲酸酯）化合物其中R1和R1'各自独立地为烷基，其中R1和R1'中的至少一个具有至少约6个碳原子，R2和R2 各自独立地是亚烷基，其中R 2和R 2'中的至少一个具有至少约3个碳原子，R 3是具有至少约2个碳原子的亚烷基，并且R 4和R 5各自独立地 是氢原子或烷基，其中R1和R1'各自含有不多于2个完全氟化的碳原子。

公开(公告)号：US07314949B2

公开(公告)日：2008-01-01

申请号：US11004682

申请日：2004-12-04

申请人： Adela Goredema ,  Rina Carlini ,  Marcel P. Breton ,  Jeffrey H. Banning ,  Eniko Toma

发明人： Adela Goredema ,  Rina Carlini ,  Marcel P. Breton ,  Jeffrey H. Banning ,  Eniko Toma

IPC分类号： C07C261/00

CPC分类号： C09D11/34 ,  C07C275/26

摘要： Disclosed are trans-1,2-cyclohexane bis(urea-urethane) compounds of the formulae wherein R1 and R′1 each, independently of the other, is an alkylene group, an arylene group, an arylalkylene group, or an alkylarylene group, R2 and R′2 each, independently of the other, is an alkyl group, an aryl group, an arylalkyl group, or an alkylaryl group, R3 and R′3 each, independently of the other, is a hydrogen atom or an alkyl group, R4 and R′4 each, independently of the other, is a hydrogen atom, a fluorine atom, an alkyl group, or a phenyl group, n is an integer of 0, 1, 2, 3, or 4, and R5 is an alkyl group, an aryl group, an arylalkyl group, an alkylaryl group, or a substituent other than an alkyl, aryl, arylalkyl, or alkylaryl group.

摘要翻译： 公开了下式的反式1,2-环己烷双（脲 - 氨基甲酸酯）化合物，其中R 1和R 2各自独立地是亚烷基 基团，亚芳基，芳基亚烷基或烷基亚芳基，R 2和R'2各自独立地是烷基，芳基 ，芳基烷基或烷基芳基，R 3和R'3各自独立地是氢原子或烷基，R 1， 4和R'4各自独立地是氢原子，氟原子，烷基或苯基，n是0,1或2的整数， 2,3或4，并且R 5是烷基，芳基，芳基烷基，烷基芳基或除烷基，芳基，芳基烷基或烷基芳基以外的取代基。

公开(公告)号：US07576235B2

公开(公告)日：2009-08-18

申请号：US11097758

申请日：2005-04-01

申请人： Rina Carlini ,  Adela Goredema ,  Eniko Toma ,  Christine E. Bedford

发明人： Rina Carlini ,  Adela Goredema ,  Eniko Toma ,  Christine E. Bedford

IPC分类号： C07C261/00 ,  C07C269/00

CPC分类号： C07C273/1854 ,  C07C2601/14 ,  C07C275/26

摘要： Processes for preparing bis(urea-urethane) compounds wherein R1 is alkyl, aryl, arylalkyl, or alkylaryl, R2 is alkylene, arylene, arylalkylene, or alkylarylene, R3 is alkylene, arylene, arylalkylene, or alkylarylene, and R4 is hydrogen or alkyl, comprising: (1) first bring to a reaction temperature of about 20-125° C. a reaction mixture comprising monoalcohol reactant R1—OH and diisocyanate reactant OCN—R2—NCO, the monoalcohol being present in an amount of about 0.8-1.2 moles monoalcohol per mole diisocyanate, the monoalcohol and diisocyanate reactants being admixed in a solvent, the reactants and solvent being present in relative amounts of at least about 1 milliliter solvent per millimole diisocyanate, the reaction temperature continuing until reaction between the monoalcohol and the diisocyanate is complete; and (2) subsequent to step (1), adding to the reaction mixture diamine without isolating the reaction product of step (1), thereby forming compound of the formula in desirably high yield and purity.

摘要翻译： 制备双（脲 - 氨基甲酸酯）化合物的方法，其中R 1是烷基，芳基，芳基烷基或烷基芳基，R 2是亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，R 3是亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，R 4是氢或烷基 包括：（1）首先使约20-125℃的反应温度，包含一元醇反应物R1-OH和二异氰酸酯反应物OCN-R2-NCO的反应混合物，一元醇的存在量为约0.8-1.2 摩尔一元醇/摩尔二异氰酸酯，一元醇和二异氰酸酯反应物在溶剂中混合，反应物和溶剂以至少约1毫升溶剂/毫摩尔二异氰酸酯的相对量存在，直到一元醇与二异氰酸酯反应的反应温度为 完成; 和（2）在步骤（1）之后，在不分离步骤（1）的反应产物的情况下向反应混合物二胺中加入，从而以期望的高产率和纯度形成式的化合物。

公开(公告)号：US20060122416A1

公开(公告)日：2006-06-08

申请号：US11004682

申请日：2004-12-04

申请人： Adela Goredema ,  Rina Carlini ,  Marcel Breton ,  Jeffrey Banning ,  Eniko Toma

发明人： Adela Goredema ,  Rina Carlini ,  Marcel Breton ,  Jeffrey Banning ,  Eniko Toma

IPC分类号： C07C275/26

CPC分类号： C09D11/34 ,  C07C275/26

摘要： Disclosed are trans-1,2-cyclohexane bis(urea-urethane) compounds of the formulae wherein R1 and R′1 each, independently of the other, is an alkylene group, an arylene group, an arylalkylene group, or an alkylarylene group, R2 and R′2 each, independently of the other, is an alkyl group, an aryl group, an arylalkyl group, or an alkylaryl group, R3 and R′3 each, independently of the other, is a hydrogen atom or an alkyl group, R4 and R′4 each, independently of the other, is a hydrogen atom, a fluorine atom, an alkyl group, or a phenyl group, n is an integer of 0, 1, 2, 3, or 4, and R5 is an alkyl group, an aryl group, an arylalkyl group, an alkylaryl group, or a substituent other than an alkyl, aryl, arylalkyl, or alkylaryl group.

摘要翻译： 公开了下式的反式1,2-环己烷双（脲 - 氨基甲酸酯）化合物，其中R 1和R 2各自独立地是亚烷基 基团，亚芳基，芳基亚烷基或烷基亚芳基，R 2和R'2各自独立地是烷基，芳基 ，芳基烷基或烷基芳基，R 3和R'3各自独立地是氢原子或烷基，R 1， 4和R'4各自独立地是氢原子，氟原子，烷基或苯基，n是0,1或2的整数， 2,3或4，并且R 5是烷基，芳基，芳基烷基，烷基芳基或除烷基，芳基，芳基烷基或烷基芳基以外的取代基。

公开(公告)号：US20060122427A1

公开(公告)日：2006-06-08

申请号：US11004331

申请日：2004-12-04

申请人： Adela Goredema ,  Rina Carlini ,  Christine Bedford ,  Marcel Breton ,  Eniko Toma

发明人： Adela Goredema ,  Rina Carlini ,  Christine Bedford ,  Marcel Breton ,  Eniko Toma

IPC分类号： C07C273/00

CPC分类号： C07C275/26 ,  C07C2601/14 ,  C09D11/34

摘要： Disclosed is a bis(urea-urethane) compound of the formula wherein R1 and R1′ each, independently of the other, is an alkyl group, wherein at least one of R1 and R1′ has at least about 6 carbon atoms, R2 and R2′ each, independently of the other, is an alkylene group, wherein at least one of R2 and R2′ has at least about 3 carbon atoms, R3 is an alkylene group having at least about 2 carbon atoms, and R4 and R5 each, independently of the other, is a hydrogen atom or an alkyl group, and wherein R1 and R1′ each contain no more than 2 fully fluorinated carbon atoms.

摘要翻译： 公开了下式的双（脲 - 氨基甲酸酯）化合物，其中R 1和R 2各自独立地是烷基，其中至少一个 的R 1和R 1'具有至少约6个碳原子，R 2和R 2各自独立地为 独立地是亚烷基，其中R 2和R 2中的至少一个具有至少约3个碳原子，R 3' / SUB>是具有至少约2个碳原子的亚烷基，R 4和R 5各自独立地是氢原子或烷基 ，并且其中R 1和R 1各自含有不超过2个完全氟化的碳原子。

公开(公告)号：US20060122415A1

公开(公告)日：2006-06-08

申请号：US11097758

申请日：2005-04-01

申请人： Rina Carlini ,  Adela Goredema ,  Eniko Toma ,  Christine Bedford

发明人： Rina Carlini ,  Adela Goredema ,  Eniko Toma ,  Christine Bedford

IPC分类号： C07C275/38

CPC分类号： C07C273/1854 ,  C07C2601/14 ,  C07C275/26

摘要： Processes for preparing bis(urea-urethane) compounds wherein R1 is alkyl, aryl, arylalkyl, or alkylaryl, R2 is alkylene, arylene, arylalkylene, or alkylarylene, R3 is alkylene, arylene, arylalkylene, or alkylarylene, and R4 is hydrogen or alkyl, comprising: (1) first bring to a reaction temperature of about 20-125° C. a reaction mixture comprising monoalcohol reactant R1—OH and diisocyanate reactant OCN—R2—NCO, the monoalcohol being present in an amount of about 0.8-1.2 moles monoalcohol per mole diisocyanate, the monoalcohol and diisocyanate reactants being admixed in a solvent, the reactants and solvent being present in relative amounts of at least about 1 milliliter solvent per millimole diisocyanate, the reaction temperature continuing until reaction between the monoalcohol and the diisocyanate is complete; and (2) subsequent to step (1), adding to the reaction mixture diamine without isolating the reaction product of step (1), thereby forming compound of the formula in desirably high yield and purity.

摘要翻译： 制备其中R 1为烷基，芳基，芳基烷基或烷基芳基的双（脲 - 氨基甲酸酯）化合物的方法是亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，R 3是亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，R 4是氢或烷基，包括：（1）首先使反应温度为约20-125℃ C.一种包含一元醇反应物R 1 -OH和二异氰酸酯反应物OCN-R 2 -NCO的反应混合物，一元醇的存在量为约0.8-1.2摩尔一元醇 每摩尔二异氰酸酯，一元醇和二异氰酸酯反应物在溶剂中混合，反应物和溶剂以至少约1毫升溶剂/毫摩尔二异氰酸酯的相对量存在，反应温度持续到一元醇和二异氰酸酯反应完成; 和（2）在步骤（1）之后，在不分离步骤（1）的反应产物的情况下向反应混合物二胺中加入，从而以期望的高产率和纯度形成式的化合物。

公开(公告)号：US20070123722A1

公开(公告)日：2007-05-31

申请号：US11290122

申请日：2005-11-30

申请人： Eniko Toma ,  Peter Odell ,  Adela Goredema ,  Jennifer Belelie

发明人： Eniko Toma ,  Peter Odell ,  Adela Goredema ,  Jennifer Belelie

IPC分类号： C07C237/02

CPC分类号： C07C233/34 ,  C07C233/36 ,  C08G69/26 ,  C09D11/101 ,  C09D11/34

摘要： Disclosed is a compound of the formula wherein R1 and R1′ each, independently of the other, is an alkyl group having at least one ethylenic unsaturation, an arylalkyl group having at least one ethylenic unsaturation, or an alkylaryl group having at least one ethylene unsaturation, R2, R2′, and R3 each, independently of the others, are alkylene groups, arylene groups, arylalkylene groups, or alkylarylene groups, and n is an integer representing the number of repeat amide units and is at least 1.

公开(公告)号：US07271284B2

公开(公告)日：2007-09-18

申请号：US11289882

申请日：2005-11-30

申请人： Eniko Toma ,  Adela Goredema ,  Jennifer L. Belelie ,  Peter G. Odell

发明人： Eniko Toma ,  Adela Goredema ,  Jennifer L. Belelie ,  Peter G. Odell

IPC分类号： C07C229/00

CPC分类号： C08F290/06 ,  C08F220/14 ,  C08F290/061 ,  C08F290/067 ,  C08G69/26 ,  C08G69/28

摘要： Disclosed is a process for preparing a compound of the formula wherein R1 is an alkyl group having at least one ethylenic unsaturation, an arylalkyl group having at least one ethylenic unsaturation, or an alkylaryl group having at least one ethylenic unsaturation, R2 and R3 each, independently of the others, are alkylene groups, arylene groups, arylalkylene groups, or alkylarylene groups, R4 and R5 each, independently of the other, is a hydrogen atom or an alkyl group, and n is an integer representing the number of repeat amide units and is at least 1, said process comprising: (a) reacting a diacid of the formula HOOC—R2—COOH with a diamine of the formula in the presence of a catalyst, a solvent, and a coupling agent to form an oligoamide intermediate; and (b) reacting the oligoamide intermediate with an alcohol of the formula R1—OH to form the product.

摘要翻译： 公开了一种制备下式化合物的方法，其中R 1是具有至少一个烯属不饱和键的烷基，具有至少一个烯属不饱和键的芳基烷基或具有至少一个烯属不饱和键的烷基芳基 R 1，R 2，R 3和R 3各自独立地是亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，R 4， 各自独立地是氢原子或烷基，n是表示重复酰胺单元数的整数，并且至少为1，所述方法包括： （a）使式（Ⅳ）的二酸与式-I-in-line-formula中的二酸反应， 在存在催化剂，溶剂和偶联剂的情况下，使式II的化合物描述=“内联式”末端=“尾”→，形成低聚酰胺中间体; 和（b）使低聚酰胺中间体与式（Ⅳ）的醇反应，其中式（Ⅳ）中，式 -line-formula description =“In-Line Formulas”end =“tail”？>来形成产品。

公开(公告)号：US07259275B2

公开(公告)日：2007-08-21

申请号：US11290328

申请日：2005-11-30

申请人： Jennifer L. Belelie ,  Adela Goredema ,  Peter G. Odell ,  Eniko Toma

发明人： Jennifer L. Belelie ,  Adela Goredema ,  Peter G. Odell ,  Eniko Toma

IPC分类号： C07C229/00

CPC分类号： C07C231/02 ,  C08G69/26 ,  C08G69/28 ,  C09D11/34 ,  C07C233/34 ,  C07C233/36

摘要： Disclosed is a process for preparing a compound of the formula wherein R1 is an alkyl group having at least one ethylenic unsaturation, an arylalkyl group having at least one ethylenic unsaturation, or an alkylaryl group having at least one ethylenic unsaturation, R2 and R3 each, independently of the others, are alkylene groups, arylene groups, arylalkylene groups, or alkylarylene groups, and n is an integer representing the number of repeat amide units and is at least 1, said process comprising: (a) reacting a diacid of the formula HOOC—R2—COOH with a diamine of the formula in the absence of a solvent while removing water from the reaction mixture to form an acid-terminated oligoamide intermediate; and (b) reacting the acid-terminated oligoamide intermediate with a monoalcohol of the formula R1—OH in the presence of a coupling agent and a catalyst to form the product.

摘要翻译： 公开了一种制备下式化合物的方法，其中R 1是具有至少一个烯属不饱和键的烷基，具有至少一个烯属不饱和键的芳基烷基或具有至少一个烯属不饱和键的烷基芳基 烯键式不饱和键，R 2和R 3各自独立地为亚烷基，亚芳基，芳基亚烷基或烷基亚芳基，n为代表 重复酰胺单元的数目并且至少为1，所述方法包括：（a）使式Ⅳ的二酸与-in-line-formula description =“In-Line Formulas”end =“lead”→> HOOC-R' 在不存在溶剂的情况下，在从反应混合物中除去水的情况下，使用下式所示的二胺，在线式描述=“In-line Formula”中， 以形成酸封端的低聚酰胺中间体; 和（b）使酸封端的低聚酰胺中间体与下式的一元醇反应：式中：=“引入”→R 1 -OH 在偶联剂和催化剂的存在下，<？in-line-formula description =“In-line formula”end =“tail”？>以形成产物。

公开(公告)号：US20070123663A1

公开(公告)日：2007-05-31

申请号：US11289882

申请日：2005-11-30

申请人： Eniko Toma ,  Adela Goredema ,  Jennifer Belelie ,  Peter Odell

发明人： Eniko Toma ,  Adela Goredema ,  Jennifer Belelie ,  Peter Odell

IPC分类号： C08F20/00

CPC分类号： C08F290/06 ,  C08F220/14 ,  C08F290/061 ,  C08F290/067 ,  C08G69/26 ,  C08G69/28

摘要： Disclosed is a process for preparing a compound of the formula wherein R1 is an alkyl group having at least one ethylenic unsaturation, an arylalkyl group having at least one ethylenic unsaturation, or an alkylaryl group having at least one ethylenic unsaturation, R2 and R3 each, independently of the others, are alkylene groups, arylene groups, arylalkylene groups, or alkylarylene groups, R4 and R5 each, independently of the other, is a hydrogen atom or an alkyl group, and n is an integer representing the number of repeat amide units and is at least 1, said process comprising: (a) reacting a diacid of the formula HOOC—R2—COOH with a diamine of the formula in the presence of a catalyst, a solvent, and a coupling agent to form an oligoamide intermediate; and (b) reacting the oligoamide intermediate with an alcohol of the formula R1—OHto form the product.