Energy efficient manufacturing process for preparing N,O-triglycidyl aminophenols

    公开(公告)号:US10023548B2

    公开(公告)日:2018-07-17

    申请号:US15310033

    申请日:2014-05-15

    IPC分类号: C07D301/24 C07D303/36

    摘要: The invention relates to an improved process for making monomeric triglycidyl compounds, wherein the triglycidyl compounds include N, O-triglycidyl compounds containing at least one primary aromatic amine and one phenolic functional group attached to the same or a different aromatic ring. The methods of the present invention result in the production of N, O-triglycidyl compounds, such as those of formula I and II. The improved process is energy efficient, environment friendly, and results in increased yields of product. The methods of the present invention can be performed in the absence of protic organic co-solvents during the reaction of an epihalohydrin with an aminophenol, such as compounds of formula II and IV, which provides an intermediate halohydrin compound. The methods of the present invention may also be performed in the absence of a phase transfer catalyst.

    IMPROVED MANUFACTURING PROCESS FOR DIHYDROXYDIPHENYLMETHANE WITH HIGH SELECTIVITY FOR 2,4'- DIHYDROXYDIPHENYLMETHANE
    2.
    发明申请
    IMPROVED MANUFACTURING PROCESS FOR DIHYDROXYDIPHENYLMETHANE WITH HIGH SELECTIVITY FOR 2,4'- DIHYDROXYDIPHENYLMETHANE 审中-公开
    用于2,4'-二羟基二苯基甲烷的高选择性的二羟基二苯基甲烷改进的制造方法

    公开(公告)号:US20160229775A1

    公开(公告)日:2016-08-11

    申请号:US15023334

    申请日:2013-09-20

    IPC分类号: C07C37/20

    摘要: The invention relates to an improved manufacturing process for the preparation of high 2, 4′-dihydroxydiphenylmethane, by a process involving reaction of phenol and formaldehyde, in the presence of an inorganic polyprotic acid. According to this process, the reaction conditions are selected to favour a high yield of dihydroxydiphenylmethane, with a relatively high concentration of the 2,4′-isomer, by using a relatively low molar excess of phenol than conventional methods.

    摘要翻译: 本发明涉及通过在无机多磷酸存在下通过苯酚和甲醛反应的方法制备高的2,4'-二羟基二苯基甲烷的改进的制备方法。 根据该方法,通过使用比常规方法使用相对低摩尔过量的苯酚,选择反应条件有利于高产率的2,4'-异构体的相对高浓度的二羟基二苯基甲烷。