公开(公告)号：US20140074213A1

公开(公告)日：2014-03-13

申请号：US14080104

申请日：2013-11-14

Applicant: Advanced Neuromodulation Systems, Inc., d/b/a St. Jude Medical Neuromodulation Division

Inventor： Hans Neisz ,  Ralph Cardinal ,  Jason J. Skubitz ,  Jason A. Shiroff

IPC: A61N1/05

CPC classification number: A61N1/0556

Abstract: Nerve cuff electrode including a tubular body having a longitudinal slit having electrodes disposed within the body. Wedge shape slits are formed into at least one of the interior wall and the exterior wall of the body, whereby the number and location of slits provided to facilitate the adjustment of the amount of compressive force of nerve cuff electrode about the nerve.

Abstract translation: 神经袖带电极包括具有设置在体内的电极的纵向狭缝的管状体。 楔形狭缝形成为主体的内壁和外壁中的至少一个，由此提供狭缝的数量和位置，以便于调节神经箍电极围绕神经的压缩力的量。

公开(公告)号：US20130041424A1

公开(公告)日：2013-02-14

申请号：US13644442

申请日：2012-10-04

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Hans Neisz

IPC: A61N1/36

CPC classification number: A61N1/36007 ,  A61N1/0509 ,  A61N1/0551

Abstract: Methods and devices for creating and/or adding to sensations of satiety to reduce food intake. Methods include electrically stimulating the duodenum which may induce false nerve signals in the duodenal region which are normally indicative of duodenal distension (fullness) and/or the presence of food in the duodenum. The artificially generated signals may be applied in a pattern which mimics at least in part a naturally occurring pattern of duodenal signals generated responsive to eating a meal. Some artificial patterns may be exaggerated relative to the natural patterns, by occurring earlier after ingestion, and/or lasting longer after ingestion, having an exaggerated (higher) frequency response or a faster rate of frequency increase after ingestion. The applied signals may generate nerve signals going to the brain which induce a feeling of satiety.

Abstract translation: 用于创造和/或增加饱腹感的方法和装置，以减少食物摄入。 方法包括电刺激十二指肠，其可能导致十二指肠区域中的假神经信号，其通常表示十二指肠膨胀（丰满度）和/或在十二指肠中存在食物。 人造产生的信号可以以至少部分地模拟响应于吃饭而产生的十二指肠信号的天然存在的模式的图案来应用。 通过在摄入之后更早地摄入和/或摄入后持续更长时间，在摄入后具有夸张（较高）频率响应或更快的频率增加速率，相对于天然模式，某些人造图案可能被夸大。 所施加的信号可能产生导致大脑饱和感的神经信号。