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公开(公告)号：US20240359013A1
公开(公告)日：2024-10-31
申请号：US18644897
申请日：2024-04-24
Applicant: Purdue Research Foundation
Inventor： Pedro Irazoqui , Gabriel Omar Albors , Daniel Pederson , Christopher John Quinkert , Muhammad Abdullah Arafat , Jack Williams , Zhi Wang , John G.R. Jefferys , Thelma Anderson Lovick , Terry L. Powley , Rebecca Anne Bercich , Henry Mei , Jesse Paul Somann , Quan Yuan , Hansraj Singh Bhamra
CPC classification number: A61N1/36135 , A61B5/01 , A61B5/08 , A61B5/14539 , A61N1/0531 , A61N1/0534 , A61N1/0548 , A61N1/0551 , A61N1/36007 , A61N1/3605 , A61N1/36053 , A61N1/36064 , A61N1/3611 , A61N1/37211 , A61N1/37223 , A61N1/3787
Abstract: Systems and techniques for wireless implantable devices, for example implantable biomedical devices employed for biomodulation. Some embodiments include a biomodulation system including a non-implantable assembly including a source for wireless power transfer and a data communications system, an implantable assembly including a power management module configured to continuously generate one or more operating voltage for the implantable assembly using wireless power transfer from the non-implantable assembly, a control module operably connected to at least one communication channel and at least one stimulation output, the control module including a processor unit to process information sensed via the at least one communication channel and, upon determining a condition exists, to generate an output to trigger the generation of a stimulus.
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2.发明公开公开(公告)号：US20240341808A1
公开(公告)日：2024-10-17
申请号：US18614512
申请日：2024-03-22
Applicant: Mainstay Medical Limited
Inventor： Jason Alan SHIROFF , Henry DEMORETT , John BECK , Sidney HAUSCHILD
CPC classification number: A61B17/3468 , A61B18/00 , A61N1/0551 , A61N1/0558 , A61B2018/00339
Abstract: Systems and methods for enhanced implantation of an electrode lead for neuromuscular electrical stimulation of tissue associated with control of the lumbar spine for treatment of back pain, in a midline-to-lateral manner are provided. The implanted lead may be secured within the patient and used to restore muscle function of local segmental muscles associated with the lumbar spine stabilization system without disruption of the electrode lead post-implantation due to anatomical structures.
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公开(公告)号：US20240335656A1
公开(公告)日：2024-10-10
申请号：US18745979
申请日：2024-06-17
Inventor： Goran N. Marnfeldt , Michael A. Moffitt
CPC classification number: A61N1/0551 , A61N1/36062 , A61N1/36071 , A61N1/36114 , A61N1/36146 , A61N1/37235
Abstract: This document discusses, among other things, systems and methods for programming neuromodulation therapy to treat neurological or cardiovascular diseases. A system includes an input circuit that receives a modulation magnitude representing a level of stimulation intensity, a memory that stores a plurality of gain functions associated with a plurality of modulation parameters, and a electrostimulator that may generate and deliver an electrostimulation therapy. A controller may program the electrostimulator with the plurality of modulation parameters based on the received modulation magnitude and the plurality of gain functions, and control the electrostimulator to generate electrostimulation therapy according to the plurality of modulation parameters.
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公开(公告)号：US20240307681A1
公开(公告)日：2024-09-19
申请号：US18672957
申请日：2024-05-23
Applicant: Wisconsin Alumni Research Foundation , Mayo Foundation for Medical Education and Research
Inventor： Justin Williams , Kip Ludwig , Erika Ross
CPC classification number: A61N1/056 , A61N1/0456 , A61N1/0476 , A61N1/0484 , A61N1/0492 , A61N1/0536 , A61N1/0551 , A61N1/36025 , A61N1/36034 , A61N1/36053 , A61N1/36067 , A61N1/36082 , A61N1/36103 , A61N1/36132 , A61N1/36146 , A61N1/36175 , A61N1/37516
Abstract: The present invention provides materials and methods for using electrical stimulation to treat a mammal having a proteinopathy (e.g., neurodegenerative diseases) or at risk of developing a proteinopathy are provided. For example, the present invention provides materials and methods for modulating glymphatic clearance (e.g., enhancing glymphatic clearance) of pathogenic proteins.
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公开(公告)号：US12090325B2
公开(公告)日：2024-09-17
申请号：US17237840
申请日：2021-04-22
Applicant: Medtronic, Inc.
Inventor： Nathan A. Torgerson
CPC classification number: A61N1/36139 , A61N1/0551 , A61N1/06 , A61N1/36034 , A61N1/36132 , A61N1/36153 , A61N1/36157 , A61N1/36185 , A61N1/37235 , A61N1/37247 , A61N1/36007 , A61N1/36021
Abstract: The techniques of the disclosure describe example medical devices, systems, and methods for delivering electrical stimulation therapy to a patient. In one example, a medical device selects subsets of a plurality of therapy parameter sets that define electrical stimulation therapy, each subset including at least one therapy parameter set and less than all of the therapy parameter sets. Further, the medical device delivers, via a plurality of electrodes, electrical stimulation therapy according to each subset via a respective set of electrodes different from sets of electrodes of each other subset of the therapy parameter sets. The medical device iteratively delivers the electrical stimulation therapy according to the subsets of the therapy parameter sets via the respective sets of electrodes. Further, the medical device selects at least one subset of the therapy parameter sets that treat a condition of the patient for defining subsequent delivery of electrical stimulation to the patient.
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Patent Agency Ranking
公开(公告)号：US12090322B2
公开(公告)日：2024-09-17
申请号：US17443172
申请日：2021-07-21
Applicant: Wavegate Corporation
Inventor： Erich W. Wolf, II
CPC classification number: A61N1/36062 , A61N1/0551 , A61N1/36071 , A61N1/36171 , A61N1/36175 , A61N1/36178
Abstract: The Randomized Intermittent Dichotomous Stimulation (RIDS) paradigm disclosed provides an alternate stimulus for the patient to attend to, besides the typical SCS signal, thus providing a somatotopically-matched non-noxious stimulus to replace the cognitive attention to the nociceptive stimulus. The randomly intermittent stimulus is paired with an implicit virtual task to reinforce selective attention to the non-noxious stimulus.
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公开(公告)号：US20240299736A1
公开(公告)日：2024-09-12
申请号：US18411246
申请日：2024-01-12
Applicant: Case Western Reserve University
Inventor： Niloy Bhadra , Narendra Bhadra , Kevin L. Kilgore , Scott Lempka , Jesse Wainright , Tina Vrabec , Manfred Franke
CPC classification number: A61N1/0551 , A61N1/06 , A61N1/20 , A61N1/36021 , A61N1/36062 , A61N1/36071 , A61N1/36125 , A61N1/0456 , A61N1/0556 , A61N1/205 , A61N1/36017 , A61N1/3615 , A61N1/36171
Abstract: Described herein are systems and methods for the treatment of pain using electrical nerve conduction block (ENCB). Contrary to other methods of pain treatment, the ENCB can establish a direct block of neural activity, thereby eliminating the pain. Additionally, the ENCB can be administered without causing electrochemical damage. An example method can include: placing at least one electrode contact in electrical communication with a region of a subject's spinal cord; applying an electrical nerve conduction block (ENCB) to a nerve in the region through the at least one electrode contact; and blocking neural activity with the ENCB to reduce the pain or other unwanted sensation in the subject.
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公开(公告)号：US12076566B2
公开(公告)日：2024-09-03
申请号：US17129467
申请日：2020-12-21
Applicant: LivaNova USA, Inc.
Inventor： Imad Libbus , Bruce H. KenKnight
IPC: A61N1/36 , A61B5/349 , A61N1/05 , A61N1/37 , A61N1/372 , G16H20/30 , G16H20/40 , G16H40/20 , G16H40/63 , G16Z99/00
CPC classification number: A61N1/36139 , A61B5/349 , A61N1/0551 , A61N1/36114 , A61N1/36132 , A61N1/3615 , A61N1/36167 , A61N1/3702 , A61N1/37223 , A61N1/37235 , G16H20/30 , G16H20/40 , G16H40/20 , G16H40/63 , G16Z99/00
Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level until a target T-wave alternans change from a baseline T-wave alternans is achieved.
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公开(公告)号：US12070598B2
公开(公告)日：2024-08-27
申请号：US17462714
申请日：2021-08-31
Inventor： Goran N. Marnfeldt , Michael A. Moffitt
CPC classification number: A61N1/0551 , A61N1/36062 , A61N1/36071 , A61N1/36114 , A61N1/36146 , A61N1/37235
Abstract: This document discusses, among other things, systems and methods for programming neuromodulation therapy to treat neurological or cardiovascular diseases. A system includes an input circuit that receives a modulation magnitude representing a level of stimulation intensity, a memory that stores a plurality of gain functions associated with a plurality of modulation parameters, and a electrostimulator that may generate and deliver an electrostimulation therapy. A controller may program the electrostimulator with the plurality of modulation parameters based on the received modulation magnitude and the plurality of gain functions, and control the electrostimulator to generate electrostimulation therapy according to the plurality of modulation parameters.
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公开(公告)号：US12064635B2
公开(公告)日：2024-08-20
申请号：US17081752
申请日：2020-10-27
Inventor： Tianhe Zhang , Changfang Zhu , Que T. Doan
CPC classification number: A61N1/36164 , A61N1/0551 , A61N1/36062 , A61N1/36071 , A61N1/36132 , A61N1/36139 , A61N1/36185 , A61N1/36189 , A61N1/37247 , A61N1/3615 , A61N1/36171 , A61N1/36175 , A61N1/36178
Abstract: An example of a system to program a neuromodulator to deliver neuromodulation to a neural target using a plurality of electrodes may comprise a programming control circuit configured to determine target energy allocations for the plurality of electrodes based on at least one target pole to provide a target sub-perception modulation field, and normalize the target sub-perception modulation field, including determine a time domain scaling factor to account for at least one property of a neural target or of a neuromodulation waveform, and apply the time domain scaling factor to the target energy allocations.
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