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公开(公告)号：US20200071406A1
公开(公告)日：2020-03-05
申请号：US16491697
申请日：2018-03-01
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Lionel Low , Angeline Goh , Bei Wang , Wen-Hsin Lee , Ching-Wen Huang
IPC: C07K16/28 , C07K16/30 , A61P35/00 , G01N33/574
Abstract: Antibodies and fragments thereof which bind to peptide-MHC complexes are described. In particular, an antibody binding to a peptide-MHC complex comprising a peptide of p53 and a MHC Class I molecule comprising α-chain encoded by an HLA-A*24 allele is claimed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods of treating, preventing and diagnosing cancers using the same.
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公开(公告)号：US10919962B2
公开(公告)日：2021-02-16
申请号：US16192537
申请日：2018-11-15
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号：US20190144535A1
公开(公告)日：2019-05-16
申请号：US16192537
申请日：2018-11-15
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-l Wang , Angeline Goh , Siok Ping Yeo , Alessandra Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: C07K16/24
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号：US11945877B2
公开(公告)日：2024-04-02
申请号：US16969119
申请日：2019-02-12
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Lionel Jianrong Low , Angeline Goh , Sandy Wen-Hsin Lee
CPC classification number: C07K16/32 , A61P35/00 , A61K2039/505 , C07K2317/33 , C07K2317/73 , C07K2317/92
Abstract: Antibodies, antigen-binding fragments and polypeptides that bind to HER2 are disclosed, as well as nucleic acids and vectors encoding the same. Also provided are cells comprising the antibodies, antigen-binding fragments, polypeptides, nucleic acids and vectors, methods of making such molecules, and the use of such molecules for therapeutic applications.
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公开(公告)号：US11912761B2
公开(公告)日：2024-02-27
申请号：US17150689
申请日：2021-01-15
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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Patent Agency Ranking
公开(公告)号：US11780913B2
公开(公告)日：2023-10-10
申请号：US17061194
申请日：2020-10-01
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号：US11702471B2
公开(公告)日：2023-07-18
申请号：US17150691
申请日：2021-01-15
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: C07K16/24 , A61K39/395 , A61K39/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号：US20210139605A1
公开(公告)日：2021-05-13
申请号：US16969119
申请日：2019-02-12
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Lionel Jianrong Low , Angeline Goh , Sandy Wen-Hsin Lee
Abstract: Antibodies, antigen-binding fragments and polypeptides that bind to HER2 are disclosed, as well as nucleic acids and vectors encoding the same. Also provided are cells comprising the antibodies, antigen-binding fragments, polypeptides, nucleic acids and vectors, methods of making such molecules, and the use of such molecules for therapeutic applications.
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公开(公告)号：US10167335B2
公开(公告)日：2019-01-01
申请号：US14378442
申请日：2013-02-13
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号：US20150037248A1
公开(公告)日：2015-02-05
申请号：US14378442
申请日：2013-02-13
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Mortellaro , Subhra Kumar , Florent Ginhoux , Pingyu Zhong
IPC: C07K16/24 , A61K39/395
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
Abstract translation: 本发明涉及抗原结合蛋白，特别是IL-1和bgr; 抗原结合蛋白。 本发明还提供了包含抗原结合蛋白的组合物，抗原结合蛋白的用途和生产方法。
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