公开(公告)号：US09493424B2

公开(公告)日：2016-11-15

申请号：US14420859

申请日：2013-08-07

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Jackie Y. Ying ,  Lihong Liu ,  Hong Wu

IPC: A61K31/787 ,  C07D233/61 ,  A01N43/50

CPC classification number: C07D233/61 ,  A01N43/50 ,  A61K31/787

Abstract: There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by hydrophobic linkers selected to confer a therapeutic effect. There is also provided the use of the above compound in the manufacture of a medicament for the treatment of a fungal infection and a method of treating a fungal infection using the above compound.

Abstract translation: 提供用于治疗的化合物，所述化合物包含亲水性杂环胺单体的重复单元，所述亲水性杂环胺单体通过被选择赋予治疗效果的疏水性接头偶联。 还提供了上述化合物在制备用于治疗真菌感染的药物中的用途以及使用上述化合物治疗真菌感染的方法。

公开(公告)号：US09802902B2

公开(公告)日：2017-10-31

申请号：US15297906

申请日：2016-10-19

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Jackie Y. Ying ,  Lihong Liu ,  Hong Wu

IPC: C07D233/61 ,  A61K31/787 ,  A01N43/50

CPC classification number: C07D233/61 ,  A01N43/50 ,  A61K31/787

Abstract: There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by hydrophobic linkers selected to confer a therapeutic effect. There is also provided the use of the above compound in the manufacture of a medicament for the treatment of a fungal infection and a method of treating a fungal infection using the above compound.

公开(公告)号：US20150203454A1

公开(公告)日：2015-07-23

申请号：US14420859

申请日：2013-08-07

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Jackie Y. Ying ,  Lihong Liu ,  Hong Wu

IPC: C07D233/61 ,  A01N43/50

CPC classification number: C07D233/61 ,  A01N43/50 ,  A61K31/787

Abstract: There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by hydrophobic linkers selected to confer a therapeutic effect. There is also provided the use of the above compound in the manufacture of a medicament for the treatment of a fungal infection and a method of treating a fungal infection using the above compound.

Abstract translation: 提供用于治疗的化合物，所述化合物包含亲水性杂环胺单体的重复单元，所述亲水性杂环胺单体通过被选择赋予治疗效果的疏水性接头偶联。 还提供了上述化合物在制备用于治疗真菌感染的药物中的用途以及使用上述化合物治疗真菌感染的方法。

公开(公告)号：US20170037013A1

公开(公告)日：2017-02-09

申请号：US15297906

申请日：2016-10-19

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Jackie Y. Ying ,  Lihong Liu ,  Hong Wu

IPC: C07D233/61

CPC classification number: C07D233/61 ,  A01N43/50 ,  A61K31/787

Abstract: There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by hydrophobic linkers selected to confer a therapeutic effect. There is also provided the use of the above compound in the manufacture of a medicament for the treatment of a fungal infection and a method of treating a fungal infection using the above compound.

Abstract translation: 提供用于治疗的化合物，所述化合物包含亲水性杂环胺单体的重复单元，所述亲水性杂环胺单体通过被选择赋予治疗效果的疏水性接头偶联。 还提供了上述化合物在制备用于治疗真菌感染的药物中的用途以及使用上述化合物治疗真菌感染的方法。