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公开(公告)号：US11331337B2
公开(公告)日：2022-05-17
申请号：US16770721
申请日：2018-12-11
Applicant: Agency for Science, Technology and Research
IPC: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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公开(公告)号：US11806362B2
公开(公告)日：2023-11-07
申请号：US17728503
申请日：2022-04-25
Applicant: Agency for Science, Technology and Research
IPC: A61K31/727
CPC classification number: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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公开(公告)号：US20220347205A1
公开(公告)日：2022-11-03
申请号：US17728503
申请日：2022-04-25
Applicant: Agency for Science, Technology and Research
IPC: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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公开(公告)号：US20210161945A1
公开(公告)日：2021-06-03
申请号：US16770721
申请日：2018-12-11
Applicant: Agency for Science, Technology and Research
Inventor： Raymond Alexander Alfred Smith , Simon McKenzie Cool , Victor Nurcombe
IPC: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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