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公开(公告)号：US10220054B2
公开(公告)日：2019-03-05
申请号：US15336407
申请日：2016-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC: A61K31/727 , A61K31/726 , A61K38/18 , C08B37/00 , A61L27/20 , A61L27/54 , A61K9/00 , A61K35/28
Abstract: Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.
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公开(公告)号：US20160375099A1
公开(公告)日：2016-12-29
申请号：US15262895
申请日：2016-09-12
Applicant: Agency for Science, Technology and Research
Inventor： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
CPC classification number: A61K38/1875 , A61K31/727 , A61K31/737 , A61K35/28 , A61K2035/124 , A61L27/26 , A61L27/365 , A61L27/3834 , A61L27/3847 , A61L27/54 , A61L2300/236 , A61L2300/252 , A61L2300/414 , A61L2430/02 , B01D15/3823 , C07K14/51 , C08B37/0003 , C08B37/0075 , C12N5/0663 , C12N2501/155 , C12N2501/90
Abstract: Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.
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公开(公告)号：US11806362B2
公开(公告)日：2023-11-07
申请号：US17728503
申请日：2022-04-25
Applicant: Agency for Science, Technology and Research
IPC: A61K31/727
CPC classification number: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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公开(公告)号：US20220347205A1
公开(公告)日：2022-11-03
申请号：US17728503
申请日：2022-04-25
Applicant: Agency for Science, Technology and Research
IPC: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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Patent Agency Ranking
公开(公告)号：US20210161945A1
公开(公告)日：2021-06-03
申请号：US16770721
申请日：2018-12-11
Applicant: Agency for Science, Technology and Research
Inventor： Raymond Alexander Alfred Smith , Simon McKenzie Cool , Victor Nurcombe
IPC: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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公开(公告)号：US20180360916A1
公开(公告)日：2018-12-20
申请号：US16020463
申请日：2018-06-27
Applicant: Agency for Science, Technology and Research
Inventor： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC: A61K38/18 , A61K31/727 , B01D15/38 , A61K31/737 , C07K14/51 , A61L27/38 , A61L27/26 , A61K35/28 , A61L27/54 , C08B37/00
Abstract: The isolation and identification of glycosaminoglycans capable of binding to proteins having a heparin-binding domain is disclosed, as well as the use of the glycosaminoglycans isolated in the growth and/or development of tissue.
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公开(公告)号：US11331337B2
公开(公告)日：2022-05-17
申请号：US16770721
申请日：2018-12-11
Applicant: Agency for Science, Technology and Research
IPC: A61K31/727
Abstract: Isolated heparin or heparan sulphate oligosaccharide fragments having a chain length of at least 10 saccharides and no more than 50 saccharides, which are capable of binding BMP2, are disclosed. Also disclosed is the use of the same heparin or heparan sulphate oligosaccharide fragments in kits and pharmaceutical compositions, and the use of the same heparan sulphate oligosaccharide fragments in the repair and/or regeneration of connective tissue and bones, and the treatment of wounds.
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公开(公告)号：US10245301B2
公开(公告)日：2019-04-02
申请号：US15262895
申请日：2016-09-12
Applicant: Agency for Science, Technology and Research
Inventor： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC: A61K31/727 , A61L27/54 , A61L27/26 , C08B37/00 , A61K38/18 , A61L27/36 , B01D15/38 , C07K14/51 , C12N5/0775 , A61K31/737 , A61K35/28 , A61L27/38 , A61K35/12
Abstract: Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.
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公开(公告)号：US20170106012A1
公开(公告)日：2017-04-20
申请号：US15336407
申请日：2016-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Simon McKenzie Cool , Victor Nurcombe , Christian Dombrowski
IPC: A61K31/727 , A61L27/54 , A61L27/20 , A61K35/28 , A61K38/18
CPC classification number: A61K31/727 , A61K9/0024 , A61K31/726 , A61K35/28 , A61K38/1875 , A61L27/20 , A61L27/54 , C08B37/0075
Abstract: Heparan sulphate HS/BMP2 is disclosed, together with the use of HS/BMP2 in the repair and regeneration of bone tissue.
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