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公开(公告)号：US11992518B2
公开(公告)日：2024-05-28
申请号：US16455224
申请日：2019-06-27
Applicant: AGILENT TECHNOLOGIES, INC.
Inventor： Jørgen Schøller , Henrik Pedersen , Liselotte Brix
CPC classification number: A61K39/00 , A61K39/12 , A61K39/21 , A61K47/61 , A61K47/646 , C07K14/70539 , A61K38/00 , A61K2039/5154 , A61K2039/54 , A61K2039/545 , A61K2039/55505 , A61K2039/55516 , A61K2039/55583 , A61K2039/6087 , A61K2039/625 , C12N2740/16134 , C12N2740/16234 , Y02A50/30
Abstract: The present invention relates to methods for construction of pharmamers i.e. vaccine components characterized by their multimerization domain and the attached biologically active molecules, and their use in preparation of vaccines that contains the pharmamers alone or in combination with other molecules. The individual molecules of the construct can be bound to each other or the multimerization domain(s) by covalent or non-covalent bonds, directly or via linkers. The invention further relates to the use of such preparations in vaccine settings aimed to function as preventive/prophylactic or therapeutic vaccines in humans and animals.
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公开(公告)号：US20240366738A1
公开(公告)日：2024-11-07
申请号：US18643793
申请日：2024-04-23
Applicant: Agilent Technologies, Inc.
Inventor： Jørgen Schøller , Henrik Pedersen , Liselotte Brix
Abstract: The present invention relates to methods for construction of pharmamers i.e. vaccine components characterized by their multimerization domain and the attached biologically active molecules, and their use in preparation of vaccines that contains the pharmamers alone or in combination with other molecules. The individual molecules of the construct can be bound to each other or the multimerization domain(s) by covalent or non-covalent bonds, directly or via linkers. The invention further relates to the use of such preparations in vaccine settings aimed to function as preventive/prophylactic or therapeutic vaccines in humans and animals.
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