公开(公告)号：US20170362186A1

公开(公告)日：2017-12-21

申请号：US15640661

申请日：2017-07-03

申请人： AiCuris GmbH & Co. KG

发明人： Welljanne MAERTENS ,  Christian SCHICKANEDER

IPC分类号： C07D239/84 ,  C07C309/30 ,  C07C309/29

CPC分类号： C07D239/84 ,  C07C309/29 ,  C07C309/30

摘要： The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl} acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses.

公开(公告)号：US20170114026A1

公开(公告)日：2017-04-27

申请号：US15338984

申请日：2016-10-31

申请人： AiCuris GmbH & Co. KG

发明人： Welljanne MAERTENS ,  Christian SCHICKANEDER

IPC分类号： C07D239/84

CPC分类号： C07D239/84 ,  C07C309/29 ,  C07C309/30

摘要： The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl}acetic acid and solvates thereof, to the use thereof in a method of treating find/or preventing virus infections, find to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses (FIG. 1).