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1.发明授权Ti-3 protein derived from triatoma infestans exhibiting activity to inhibit platelet aggregation 失效衍生自表达抑制血小板聚集的活性的三病毒感染者的Ti-3蛋白公开(公告)号：US06956106B2
公开(公告)日：2005-10-18
申请号：US10401038
申请日：2003-03-28
申请人： Akihiro Morita , Haruhiko Isawa , Masao Yuda , Yuki Orito , Yasuo Chinzei
发明人： Akihiro Morita , Haruhiko Isawa , Masao Yuda , Yuki Orito , Yasuo Chinzei
IPC分类号： C12N15/09 , A61K38/00 , A61P7/02 , C07K14/435 , C07K14/705
CPC分类号： C07K14/43563
摘要： The present invention provides Ti-3 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-3 gene encoding the protein. As the Ti-3 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-3 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-3 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.
摘要翻译： 本发明提供Ti-3蛋白，其是从致病性三病毒细胞的唾液腺获得的蛋白质，本发明提供编码该蛋白质的Ti-3基因。 由于Ti-3蛋白质对血小板聚集具有抑制活性，所以含有作为活性成分的Ti-3蛋白质的药物可以作为预防和治疗心肌梗塞，肺梗塞，脑梗死的血小板聚集抑制剂。 此外，Ti-3蛋白也将作为新型血小板聚集抑制剂开发中的高度前瞻性铅化合物。
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2.发明授权Ti-4 protein derived from Triatoma infestans exhibiting activity to inhibit platelet aggregation 失效衍生自表达抑制血小板聚集的活性的三病毒感染者的Ti-4蛋白公开(公告)号：US07084254B2
公开(公告)日：2006-08-01
申请号：US10401141
申请日：2003-03-28
申请人： Akihiro Morita , Haruhiko Isawa , Masao Yuda , Yuki Orito , Yasuo Chinzei
发明人： Akihiro Morita , Haruhiko Isawa , Masao Yuda , Yuki Orito , Yasuo Chinzei
CPC分类号： C07H21/04 , C07K14/43563
摘要： The present invention provides Ti-4 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-4 gene encoding the protein. As the Ti-4 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-4 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-4 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.
摘要翻译： 本发明提供Ti-4蛋白，其是从致病性三病毒细胞的唾液腺获得的蛋白质，本发明提供编码该蛋白质的Ti-4基因。 由于Ti-4蛋白质对血小板聚集具有抑制活性，所以含有作为活性成分的Ti-4蛋白质的药物可以作为预防和治疗心肌梗死，肺梗死，脑梗死的血小板聚集抑制剂。 此外，Ti-4蛋白也将作为新型血小板聚集抑制剂开发中的高度前瞻性铅化合物。
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