公开(公告)号：US20050187581A1

公开(公告)日：2005-08-25

申请号：US11014461

申请日：2004-12-17

申请人： Akikuni Hara ,  Hiroyuki Hara ,  Naoyoshi Suzuki ,  Shinji Harakawa ,  Nobuo Uenaka ,  David Martin ,  Henry Harris

发明人： Akikuni Hara ,  Hiroyuki Hara ,  Naoyoshi Suzuki ,  Shinji Harakawa ,  Nobuo Uenaka ,  David Martin ,  Henry Harris

IPC分类号： A61N1/00

CPC分类号： A61N1/00

摘要： The invention relates to methods and devices for treating disorders with electric current or electric field therapy. The invention uses applied electric current or current induced by an external electric field to alter ionic concentrations and modulates at least one G-protein-coupled receptor. The invention is useful, for example, for treating hyperproliferative and cardiovascular disorders and for ameliorating the effects of stress.

摘要翻译： 本发明涉及用电流或电场治疗来治疗疾病的方法和装置。 本发明使用施加的电流或由外部电场引起的电流来改变离子浓度并调节至少一种G蛋白偶联受体。 本发明例如用于治疗过度增生和心血管疾病以及改善压力的作用是有用的。

公开(公告)号：US20070260290A1

公开(公告)日：2007-11-08

申请号：US11596315

申请日：2005-05-10

申请人： Akikuni Hara ,  Masayoshi Yukawa ,  Masato Kuwabara ,  Shinji Harakawa ,  Takuya Hori ,  Fuyuki Doge

发明人： Akikuni Hara ,  Masayoshi Yukawa ,  Masato Kuwabara ,  Shinji Harakawa ,  Takuya Hori ,  Fuyuki Doge

IPC分类号： A61N1/10 ,  A61D1/10 ,  A61N1/40

CPC分类号： A61N1/10 ,  A61N1/40

摘要： The present invention relates to a method of treating or improving rheumatism and pain caused by rheumatism, tumor, and spinal damage of mammalian animals by a non-pharmacological method. Extremely low AC electric field with DC electric field overlapped is exposed to a whole or a part of mammalian animals with electrodes in a non-contact state. In the exposure of the above mentioned electric field, said electric field is exposed for a certain period of time a day, repeating this everyday or once a week. Further, as required, frequency of the electric field, voltage to be applied, exposure time, and the like are controlled.

摘要翻译： 本发明涉及通过非药理学方法治疗或改善由哺乳动物的风湿病，肿瘤和脊髓损伤引起的风湿病和疼痛的方法。 具有直流电场重叠的极低交流电场暴露于具有非接触状态的电极的哺乳动物的全部或部分。 在上述电场的曝光中，所述电场每天暴露一定时间，每天或每周重复一次。 此外，根据需要，控制电场频率，施加电压，曝光时间等。

公开(公告)号：US07081362B2

公开(公告)日：2006-07-25

申请号：US10476778

申请日：2002-06-25

申请人： Fuyuki Doge ,  Katsuo Isaka ,  Akikuni Hara

发明人： Fuyuki Doge ,  Katsuo Isaka ,  Akikuni Hara

IPC分类号： C12M1/12

CPC分类号： C12M35/02

摘要： A culture apparatus and cultivation method are provided which enable liquid materials such as cells or blood plasma to be evenly cultivated by making current density uniform.The culture apparatus comprises a vessel 14 having a predetermined capacity with a lower electrode 16 placed on its bottom, a cover 17 disposed in a vertically opposite direction to the vessel 14 for hermetically sealing the vessel 14 by covering the vessel 14 from above and comprising an upper electrode 18 provided opposite to the lower electrode 16, a culturing member 20 fit into the vessel 14 comprising almost in its center a hollow 21 that has a capacity made by a predetermined cross section area; a filter 25 provided between the vessel 14 and the culturing member 20, and a power source device for applying a predetermined voltage to the lower electrode 16 and the upper electrode 18 to let a current flow between the both electrodes.

摘要翻译： 提供了一种通过使电流密度均匀地均匀地培养细胞或血浆等液体材料的培养装置和培养方法。 培养装置包括具有预定容量的容器14，下部电极16放置在其底部;盖17，其设置在与容器14垂直相反的方向上，用于通过从上方覆盖容器14来密封容器14，并且包括 与下部电极16相对设置的上部电极18，装配在容器14中的培养构件20，该容器14几乎在其中心包括具有由规定截面积制成的容积的中空部21; 设置在容器14和培养部件20之间的过滤器25，以及用于向下部电极16和上部电极18施加规定电压以使电流在两个电极之间流动的电源装置。

公开(公告)号：US06792132B1

公开(公告)日：2004-09-14

申请号：US09601507

申请日：2000-08-02

申请人： Akikuni Hara ,  Toshimitsu Asano ,  Yoshiaki Torai ,  Akihiro Omi

发明人： Akikuni Hara ,  Toshimitsu Asano ,  Yoshiaki Torai ,  Akihiro Omi

IPC分类号： G06K900

CPC分类号： G01N15/0227 ,  G01N1/30 ,  G01N2015/0088 ,  G01N2015/0216

摘要： A method and an apparatus for inspecting microbes, etc. including, as an apparatus for detecting microbes, etc., a cultivating device, an image taking-in device, and an arithmetic processing unit, in which an image of a medium to be inspected obtained from a sample collected from a substance or a physical solid having proper color microbes or the medium subjected to illumination treatment, dyeing treatment, etc. prior to or after cultivation in accordance with necessity is separated into the three primary colors, or the like, then, chromatic information of histogram, color and hue for each primary color are calculated, and the information thus obtained is compared with integrated data obtained by combining second data of generic information of microbes, etc. with first data of microbes, etc. which are preliminarily accumulated in the same procedure as the above, so that the features specific to microbes are extracted for identification of the kind of the microbes, and a state of propagation of the microbes after the passage of a predetermined time is anticipated, thereby a state of propagation of the microbes after the passage of a predetermined time required for cultivation of microbes in the medium can preliminarily be detected make anticipate in a short time.

摘要翻译： 检测微生物等的方法和装置，包括作为检测微生物的装置等的培养装置，图像摄取装置和运算处理单元，其中待检查的培养基的图像 从具有适当的颜色微生物的物质或物理固体收集的样品或根据需要培养之前或之后进行照明处理，染色处理等的样品分离为三原色等， 然后，计算每个原色的直方图，颜色和色调的色度信息，并将所获得的信息与通过将微生物的一般信息等的第二数据与微生物等的第一数据组合而获得的综合数据进行比较， 以与上述相同的程序预先累积，从而提取微生物特有的特征以识别微生物的种类，并且传播状态 预期经过预定时间之后的微生物的预期，从而可以预先检测微生物在介质中培养微生物所需的预定时间通过后微生物的繁殖状态。

公开(公告)号：US4802470A

公开(公告)日：1989-02-07

申请号：US22529

申请日：1987-03-02

申请人： Akikuni Hara ,  Yukio Ogawa

发明人： Akikuni Hara ,  Yukio Ogawa

IPC分类号： A61N1/10 ,  A61N1/40 ,  A61N1/00

CPC分类号： A61N1/10 ,  A61N1/40

摘要： An electric field therapy apparatus having electrodes connected to a pair of output terminals characterized in that an intermediate point between the output terminals is connected, as a voltage point, ground. With this arrangement, each of the electrodes can be constructed so as to make withstand voltage to ground small, and the electric potential difference between the electrodes can be made large.

摘要翻译： 一种具有连接到一对输出端子的电极的电场治疗装置，其特征在于，连接作为电压点的输出端子之间的中间点接地。 通过这种布置，可以构造各电极，使得对地的耐电压小，能够使电极间的电位差大。