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    HISTOFLUORESCENT STAIN COMPOSITION FOR ENDOSCOPY
    2.
    发明申请
    HISTOFLUORESCENT STAIN COMPOSITION FOR ENDOSCOPY 审中-公开
    用于内窥镜的感染性不良组合物

    公开(公告)号：US20080045796A1

    公开(公告)日：2008-02-21

    申请号：US11758688

    申请日：2007-06-06

    申请人： Akira YAMAMOTO ,  Yusuke IIMORI ,  Mizue SAZE ,  Mariko ISHIGURO ,  Pilryon LEE ,  Hiroyuki SASAKI

    发明人： Akira YAMAMOTO ,  Yusuke IIMORI ,  Mizue SAZE ,  Mariko ISHIGURO ,  Pilryon LEE ,  Hiroyuki SASAKI

    IPC分类号： A61B1/00 ,  A61K49/00

    CPC分类号： A61K49/0023

    摘要： A fluorescent stain which has a function of clarifying the shape of the surface of the gastrointestinal lumen in the visible light wavelength region, and simultaneously, emitting fluorescence by being excited by light of a specific wavelength, and which is also biologically safe and is suitable for endoscopic observation, is provided. A histofluorescent stain composition for endoscopy, containing a compound represented by the following Formula (1): wherein R1 represents a hydrogen atom or a hydroxyl group; R3 represents a phenyl group or methyl group, to which R2c is bound; one to three of R2a, R2b and R2c represent —SO3M (wherein M represents an alkali metal atom or an alkaline earth metal atom), or —SO3NH4, and when one represents —SO3−, the others represent hydrogen atoms is provided.

    摘要翻译： 具有澄清可见光波长区域的胃肠腔表面形状的荧光染料，同时通过被特定波长的光激发而发出荧光，并且也具有生物学安全性，适用于 提供内窥镜观察。 用于内窥镜检查的组织荧光染色组合物，其含有由下式（1）表示的化合物：其中R 1表示氢原子或羟基; R 3表示R 2c结合的苯基或甲基; R 2a，R 2b和R 2c中的一个至三个表示-SO 3 M（其中M表示 碱金属原子或碱土金属原子）或-SO 3 NH 4，当一个表示-SO 3 - ，其他代表氢原子。

    AGENT FOR ENHANCING CONTRAST OF IMAGE OF FLUORESCENT STAINING OF LUMEN OF DIGESTIVE TRACT
    3.
    发明申请
    AGENT FOR ENHANCING CONTRAST OF IMAGE OF FLUORESCENT STAINING OF LUMEN OF DIGESTIVE TRACT 有权
    用于增强消毒剂的荧光素染色图像对比度的试剂

    公开(公告)号：US20080008656A1

    公开(公告)日：2008-01-10

    申请号：US11762961

    申请日：2007-06-14

    申请人： Akira YAMAMOTO ,  Yusuke IIMORI ,  Mizue SAZE ,  Mariko ISHIGURO ,  Pilryon LEE

    发明人： Akira YAMAMOTO ,  Yusuke IIMORI ,  Mizue SAZE ,  Mariko ISHIGURO ,  Pilryon LEE

    IPC分类号： A61K49/00 ,  A61P43/00

    CPC分类号： A61K49/0043 ,  A61K49/0071

    摘要： It is intended to provide means for more clearly showing an image of fluorescent staining of a lumen of the digestive tract. The present invention provides an agent for enhancing a contrast of an image of fluorescent staining of a lumen of the digestive tract with an intravenously administered fluorescent dye, wherein the agent for enhancing a contrast is an agent for a lumen of the digestive tract containing an aqueous solution having a buffer capacity and having a pH of 6 to 10.

    摘要翻译： 旨在提供用于更清楚地显示消化道的内腔的荧光染色的图像的装置。 本发明提供了一种用于增强消化道腔的荧光染色的图像与静脉内施用的荧光染料的对比度的试剂，其中用于增强对比度的药剂是含有水性的消化道的内腔的药剂 具有缓冲能力并且pH为6至10的溶液。