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    Tunable magneto-rheological elastomers and processes for their manufacture
    7.
    发明申请
    Tunable magneto-rheological elastomers and processes for their manufacture 失效
    可调谐磁流变弹性体及其制造方法

    公开(公告)号：US20050116194A1

    公开(公告)日：2005-06-02

    申请号：US10851997

    申请日：2004-05-20

    申请人： Alan Fuchs ,  Faramarz Gordaninejad ,  Gregory Hitchcock ,  Jacob Elkins ,  Qi Zhang

    发明人： Alan Fuchs ,  Faramarz Gordaninejad ,  Gregory Hitchcock ,  Jacob Elkins ,  Qi Zhang

    IPC分类号： F16F1/36 ,  H01F1/28

    CPC分类号： F16F1/3615 ,  F16F1/3605 ,  F16F2224/0283

    摘要： Novel magnetorheological elastomer compositions are provided. The magnetorheological elastomers (MREs) may have aligned or randomly arranged magnetizable particles in a thermoset or thermoplastic matrix. The magnetizable particles may be coated to reduce corrosion and/or improve bonding between the particle and the matrix. The magnetizable particles may be flake-shaped. The MREs may have matrices selected from the group consisting of hydrogenated nitrile rubbers, butyl rubbers, ethylene-propylene copolymers and terpolymers, ethylene-acrylic copolymers, fluorinated elastomers, silphenylene-siloxanes, silarylene-siloxanes, poly(carborane-siloxane-acetylene)s and blends thereof. The MREs may also have matrices selected from the group consisting of styrene-butadiene block copolymers, copolyesters, polyamides, polyether block amides, polyolefin-elastomers other than polyalpha olefins, chlorinated polyethylenes, ionomers, chlorosulfonated polyethylenes, blends thereof, and blends of thermoplastic polyurethane with polyvinyl chloride (PVC), polyvinylindene fluoride (PVDF), polycarbonate, or acrylonitrile butadiene styrene (ABS).

    摘要翻译： 提供了新的磁流变弹性体组合物。 磁流变弹性体（MRE）可以在热固性或热塑性基质中具有对准或随机排列的可磁化颗粒。 可磁化颗粒可以被涂覆以减少腐蚀和/或改善颗粒和基质之间的粘合。 可磁化颗粒可以是片状的。 MRE可以具有选自氢化丁腈橡胶，丁基橡胶，乙烯 - 丙烯共聚物和三元共聚物，乙烯 - 丙烯酸共聚物，氟化弹性体，硅亚烷基 - 硅氧烷，亚磺酰基 - 硅氧烷，聚（碳硼烷 - 硅氧烷 - 乙炔） 和它们的混合物。 MRE还可以具有选自苯乙烯 - 丁二烯嵌段共聚物，共聚酯，聚酰胺，聚醚嵌段酰胺，除聚α烯烃以外的聚烯烃 - 弹性体，氯化聚乙烯，离聚物，氯磺化聚乙烯，其共混物，以及热塑性聚氨酯 聚氯乙烯（PVC），聚二氟乙烯氟化物（PVDF），聚碳酸酯或丙烯腈丁二烯苯乙烯（ABS）。

    MAGNETORHEOLOGICAL FLUIDS AND THERAPEUTIC USES THEREOF
    8.
    发明申请
    MAGNETORHEOLOGICAL FLUIDS AND THERAPEUTIC USES THEREOF 审中-公开
    磁流体流体及其治疗用途

    公开(公告)号：US20100063346A1

    公开(公告)日：2010-03-11

    申请号：US12300843

    申请日：2007-05-17

    申请人： William J. Murphy ,  Lisbeth A. Welniak ,  Cahit Evrensel ,  Alan Fuchs ,  Faramarz Gordaninejad

    发明人： William J. Murphy ,  Lisbeth A. Welniak ,  Cahit Evrensel ,  Alan Fuchs ,  Faramarz Gordaninejad

    IPC分类号： A61N2/00

    CPC分类号： A61K33/26 ,  A61K38/2013 ,  A61K41/0052 ,  A61K45/06

    摘要： In some embodiments, the present disclosure provides methods for stimulating a subject's immune system. Particular methods provide a tumor specific immune response by injecting a tumor with a magnetorheological fluid and applying a magnetic field to the tumor. The immune response can be used to treat disseminated tumors or metastatic cells. Further methods induce a general immune response, such as by treating a section of tissue, such as healthy tissue, with a magnetorheological fluid and applying a magnetic field to the treated tissue. The immune response can be used to treat illness or disease or to enhance the effect of a therapeutic agent. In particular examples, the disclosed methods are used to enhance the effect of immuno stimulants. Also provided are methods for causing necrosis of a cell mass, such as a tumor, by injecting a magnetorheological fluid into a section of tissue and applying a magnetic field to the tissue.

    摘要翻译： 在一些实施方案中，本公开提供了刺激受试者的免疫系统的方法。 特定的方法通过用磁流变流体注射肿瘤并向肿瘤施加磁场来提供肿瘤特异性免疫应答。 免疫应答可用于治疗弥漫性肿瘤或转移细胞。 其它方法诱导一般的免疫应答，例如通过用磁流变流体处理一部分组织，例如健康组织，并向处理的组织施加磁场。 免疫应答可用于治疗疾病或疾病或增强治疗剂的作用。 在具体实例中，所公开的方法用于增强免疫兴奋剂的效果。 还提供了通过将磁流变流体注射到组织的一部分并向组织施加磁场来引起细胞块如肿瘤的坏死的方法。

    Controllable magneto-rheological elastomer vibration isolator
    9.
    发明申请
    Controllable magneto-rheological elastomer vibration isolator 失效
    可控磁流变弹性体隔振器

    公开(公告)号：US20050011710A1

    公开(公告)日：2005-01-20

    申请号：US10844040

    申请日：2004-05-12

    申请人： Gregory Hitchcock ,  Faramarz Gordaninejad ,  Alan Fuchs

    发明人： Gregory Hitchcock ,  Faramarz Gordaninejad ,  Alan Fuchs

    IPC分类号： F16F1/36 ,  F16F9/53

    CPC分类号： F16F1/3615 ,  F16F1/361 ,  F16F2224/0283

    摘要： A tunable vibration isolation device comprising a magneto-rheological elastomer (MRE), and methods of using such a device, are provided. By manipulating a magnetic field within the MRE the device's stiffness is controlled. The vibration isolator can be constructed to provide shock absorption in one, two and three dimensions. Coupling the tunable device to a sensor feedback and a control system provides fast and accurate vibration isolation and energy dissipation for shock events in a variety of applications.

    摘要翻译： 提供了包括磁流变弹性体（MRE）的可调谐隔振装置以及使用这种装置的方法。 通过操纵MRE内的磁场，控制装置的刚度。 振动隔离器可以构造成在一个，两个和三个维度上提供减震。 将可调谐设备耦合到传感器反馈和控制系统，为各种应用中的冲击事件提供快速，准确的隔振和能量消耗。

    Tunable magneto-rheological elastomers and processes for their manufacture
    10.
    发明授权
    Tunable magneto-rheological elastomers and processes for their manufacture 失效
    可调谐磁流变弹性体及其制造方法

    公开(公告)号：US07261834B2

    公开(公告)日：2007-08-28

    申请号：US10851997

    申请日：2004-05-20

    申请人： Alan Fuchs ,  Faramarz Gordaninejad ,  Gregory H. Hitchcock ,  Jacob Elkins ,  Qi Zhang

    发明人： Alan Fuchs ,  Faramarz Gordaninejad ,  Gregory H. Hitchcock ,  Jacob Elkins ,  Qi Zhang

    IPC分类号： H01F1/44

    CPC分类号： F16F1/3615 ,  F16F1/3605 ,  F16F2224/0283

    摘要： Novel magnetorheological elastomer compositions are provided. The magnetorheological elastomers (MREs) may have aligned or randomly arranged magnetizable particles in a thermoset or thermoplastic matrix. The magnetizable particles may be coated to reduce corrosion and/or improve bonding between the particle and the matrix. The magnetizable particles may be flake-shaped. The MREs may have matrices selected from the group consisting of hydrogenated nitrile rubbers, butyl rubbers, ethylene-propylene copolymers and terpolymers, ethylene-acrylic copolymers, fluorinated elastomers, silphenylene-siloxanes, silarylene-siloxanes, poly(carborane-siloxane-acetylene)s and blends thereof. The MREs may also have matrices selected from the group consisting of styrene-butadiene block copolymers, copolyesters, polyamides, polyether block amides, polyolefin-elastomers other than polyalpha olefins, chlorinated polyethylenes, ionomers, chlorosulfonated polyethylenes, blends thereof, and blends of thermoplastic polyurethane with polyvinyl chloride (PVC), polyvinylindene fluoride (PVDF), polycarbonate, or acrylonitrile butadiene styrene (ABS).

    摘要翻译： 提供了新的磁流变弹性体组合物。 磁流变弹性体（MRE）可以在热固性或热塑性基质中具有对准或随机排列的可磁化颗粒。 可磁化颗粒可以被涂覆以减少腐蚀和/或改善颗粒和基质之间的粘合。 可磁化颗粒可以是片状的。 MRE可以具有选自氢化丁腈橡胶，丁基橡胶，乙烯 - 丙烯共聚物和三元共聚物，乙烯 - 丙烯酸共聚物，氟化弹性体，硅亚烷基 - 硅氧烷，亚磺酰基 - 硅氧烷，聚（碳硼烷 - 硅氧烷 - 乙炔） 和它们的混合物。 MRE还可以具有选自苯乙烯 - 丁二烯嵌段共聚物，共聚酯，聚酰胺，聚醚嵌段酰胺，除聚α烯烃以外的聚烯烃 - 弹性体，氯化聚乙烯，离聚物，氯磺化聚乙烯，其共混物，以及热塑性聚氨酯 聚氯乙烯（PVC），聚二氟乙烯氟化物（PVDF），聚碳酸酯或丙烯腈丁二烯苯乙烯（ABS）。