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公开(公告)号:US20090048200A1
公开(公告)日:2009-02-19
申请号:US12090741
申请日:2006-10-30
申请人: Alan Hendrick , John Dixon , Tere Michelle Tait , Rosa Fradley , Malcolm Sheardown , Haiping Liu , Kok Siu Foo
发明人: Alan Hendrick , John Dixon , Tere Michelle Tait , Rosa Fradley , Malcolm Sheardown , Haiping Liu , Kok Siu Foo
IPC分类号: A61K31/7088 , G01N33/00 , C12Q1/02 , A61P25/00 , A01K67/027 , C12Q1/68
CPC分类号: C07K14/723 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0356 , A61K48/00 , C07K14/705 , C12N15/8509 , G01N33/6896 , G01N2333/726 , G01N2500/04 , G01N2800/30
摘要: We disclose GPR26 G-protein coupled receptor (GPCR) polypeptides comprising the amino acid sequence shown in SEQ ID NO. 3 or SEQ ID NO: 5, and homologues, variants and derivatives thereof. Nucleic acids capable of encoding GPR26 polypeptide are also disclosed. The GPR26 receptor is useful in the diagnosis and therapy of mental illness.
摘要翻译: 我们公开了包含SEQ ID NO:1所示的氨基酸序列的GPR26G-蛋白偶联受体(GPCR)多肽。 3或SEQ ID NO:5,及其同源物,变体和衍生物。 还公开了能够编码GPR26多肽的核酸。 GPR26受体可用于精神疾病的诊断和治疗。