公开(公告)号：US20240350482A1

公开(公告)日：2024-10-24

申请号：US18595808

申请日：2024-03-05

申请人： Albert Einstein College of Medicine ,  The University of Manitoba

发明人： Evripidis Gavathiotis ,  Richard N. Kitsis ,  Thomas Peter Garner ,  Dulguun Amgalan ,  Lorrie Kirshenbaum ,  Felix Kopp

IPC分类号： A61K31/496 ,  A61K31/495 ,  C07D209/86 ,  C07D209/88 ,  C07D279/26 ,  C07D295/13

CPC分类号： A61K31/496 ,  A61K31/495 ,  C07D209/86 ,  C07D209/88 ,  C07D279/26 ,  C07D295/13

摘要： Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.

公开(公告)号：US11938128B2

公开(公告)日：2024-03-26

申请号：US16492300

申请日：2018-03-09

申请人： Albert Einstein College of Medicine ,  The University of Manitoba

发明人： Evripidis Gavathiotis ,  Richard N. Kitsis ,  Thomas P. Garner ,  Dulguun Amgalan ,  Lorrie Kirshenbaum ,  Felix Kopp

IPC分类号： A61K31/496 ,  A61K31/495 ,  C07D209/86 ,  C07D209/88 ,  C07D279/26 ,  C07D295/13

CPC分类号： A61K31/496 ,  A61K31/495 ,  C07D209/86 ,  C07D209/88 ,  C07D279/26 ,  C07D295/13

摘要： Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.

公开(公告)号：US20200009132A1

公开(公告)日：2020-01-09

申请号：US16492300

申请日：2018-03-09

申请人： Albert Einstein College of Medicine ,  The University of Manitoba

发明人： Evripidis Gavathiotis ,  Richard N. Kitsis ,  Thomas Peter Garner ,  Dulguun Amgalan ,  Lorrie Kirshenbaum ,  Felix Kopp

IPC分类号： A61K31/496 ,  A61K31/495

摘要： Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.