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公开(公告)号：US20230035072A1
公开(公告)日：2023-02-02
申请号：US17784579
申请日：2020-12-11
Applicant: Alector LLC
Inventor： Robert PAUL , Michael F. WARD , Hua LONG , Shiao-Ping LU , Omer Rizwan SIDDIQUI , Arnon ROSENTHAL
Abstract: The present disclosure is generally directed to antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics. The present disclosure is further directed to the methods of treating and/or delaying the progression of a disease or injury in an individual by administering such antibodies.
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