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公开(公告)号：US20240101681A1
公开(公告)日：2024-03-28
申请号：US18039945
申请日：2021-12-01
Applicant: Alector LLC
Inventor： Arnon ROSENTHAL , Felix Leejia YEH , Michael F. WARD , Robert PAUL , Hua LONG , Yijie LIAO
IPC: C07K16/28 , A61K39/395 , A61K45/06
CPC classification number: C07K16/286 , A61K39/3955 , A61K45/06 , A61K2039/505
Abstract: The present disclosure is generally directed to the use of antibodies that specifically bind one or more epitopes within a sortilin protein, e.g., human sortilin or mammalian sortilin, for treating and/or delaying progression of a disease, disorder, or injury in an individual in need thereof.
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Patent Agency Ranking
公开(公告)号：US20230035072A1
公开(公告)日：2023-02-02
申请号：US17784579
申请日：2020-12-11
Applicant: Alector LLC
Inventor： Robert PAUL , Michael F. WARD , Hua LONG , Shiao-Ping LU , Omer Rizwan SIDDIQUI , Arnon ROSENTHAL
Abstract: The present disclosure is generally directed to antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics. The present disclosure is further directed to the methods of treating and/or delaying the progression of a disease or injury in an individual by administering such antibodies.
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公开(公告)号：US20230183341A1
公开(公告)日：2023-06-15
申请号：US17916728
申请日：2021-04-02
Applicant: Alector LLC
Inventor： Robert PAUL , Michael F. WARD , Hua LONG , Omer Rizwan SIDDIQUI , Arnon ROSENTHAL , Felix Leejia YEH , Sam JACKSON
CPC classification number: C07K16/2803 , A61P25/28 , A61K2039/505
Abstract: The present disclosure is generally directed to the use of compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a TREM2 protein, e.g., human TREM2, for use in treating and/or delaying progression of a disease or injury in an individual in need thereof.
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公开(公告)号：US20230024528A1
公开(公告)日：2023-01-26
申请号：US17782127
申请日：2020-12-04
Applicant: Alector LLC
Inventor： Tina SCHWABE , Ilaria TASSI , Arnon ROSENTHAL , Hua LONG , Santiago Viveros SALAZAR
Abstract: The present disclosure is generally directed to the use of anti-TREM2 antibodies in preventing, reducing risk, or treating disease in an individual in need thereof.
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公开(公告)号：US20210079074A1
公开(公告)日：2021-03-18
申请号：US16943123
申请日：2020-07-30
Applicant: Alector LLC
Inventor： Jeonghoon SUN , Wei-Hsien HO , Muhammad A. ALHAWAGRI , Philip Ling KONG , Herve RHINN , Hua LONG , Karpagam SRINIVASAN , Ananya MITRA , Daniel P. BERMINGHAM , Klaus-Dieter HEGER , Santiago Viveros SALAZAR , Francesca CIGNARELLA , Ilaria TASSI , Tina SCHWABE , Angie Grace YEE , Arnon ROSENTHAL
IPC: C07K16/18
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20240076362A1
公开(公告)日：2024-03-07
申请号：US18310207
申请日：2023-05-01
Applicant: Alector LLC
Inventor： Jeonghoon SUN , Wei-Hsien HO , Muhammad A. ALHAWAGRI , Philip Ling KONG , Herve RHINN , Hua LONG , Karpagam SRINIVASAN , Ananya MITRA , Daniel P. BERMINGHAM , Klaus-Dieter HEGER , Santiago Viveros SALAZAR , Francesca CIGNARELLA , Ilaria TASSI , Tina SCHWABE , Angie Grace YEE , Arnon ROSENTHAL
IPC: C07K16/18
CPC classification number: C07K16/18 , A61K2039/505
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, humanized antibodies and antibody fragments, that specifically bind a MS4A4A polypeptide, e.g., a mammalian MS4A4A or human MS4A4A, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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