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公开(公告)号:US20060264610A1
公开(公告)日:2006-11-23
申请号:US10521748
申请日:2003-07-18
CPC分类号: C12N9/1029 , A01K2217/05 , A61K38/00 , C07K14/4705 , C07K2319/00
摘要: The present invention relates to the TIP60-transcriptional activator protein complex, which is a part of the beta-amyloid precursor protein (APP) processing pathway, component proteins of the said complexes, fragments and derivatives of the component proteins, and antibodies specific to the complexes. The present invention also relates to methods for use of these complexes and the interacting proteins in, inter alia, screening, diagnosis, and therapy, as well as to methods of preparing the complexes.
摘要翻译: 本发明涉及TIP60-转录激活蛋白复合物,其是β-淀粉样蛋白前体蛋白(APP)加工途径的一部分,所述复合物的组分蛋白,组分蛋白的片段和衍生物以及对 复合物。 本发明还涉及使用这些复合物和相互作用蛋白质,尤其是筛选,诊断和治疗以及制备复合物的方法。