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1.Amorphous Erlotinib, processes for the preparation thereof, and processes to prepare additional forms of Erlotinib 审中-公开
标题翻译: 无定形埃罗替尼,其制备方法和制备另外形式的厄洛替尼的方法公开(公告)号:US20090012295A1
公开(公告)日:2009-01-08
申请号:US12215251
申请日:2008-06-25
IPC分类号: C07D239/72
CPC分类号: C07D239/94
摘要: The present invention provides amorphous erlotinib, processes for the preparation thereof, and processes to prepare additional forms of erlotinib.
摘要翻译: 本发明提供无定形厄洛替尼,其制备方法和制备另外形式的厄洛替尼的方法。
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公开(公告)号:US20090124642A1
公开(公告)日:2009-05-14
申请号:US12229682
申请日:2008-08-25
申请人: Augusto Canavesi , Marco Villa , Ales Gavenda , Jiri Faustmann , Judith Aronhime , Ettore Gibatti , Alexandr Jegorov
发明人: Augusto Canavesi , Marco Villa , Ales Gavenda , Jiri Faustmann , Judith Aronhime , Ettore Gibatti , Alexandr Jegorov
IPC分类号: A61K31/517 , C07D239/94
CPC分类号: C07D239/94
摘要: The invention provides a novel crystalline form of Erlotinib HCl, processes for its preparation, and formulations thereof.
摘要翻译: 本发明提供了一种新型的埃罗替尼盐酸结晶形式,其制备方法及其制剂。
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3.Process for the preparation of crystalline forms A, B and pure crystalline form a of erlotinib HCI 审中-公开
标题翻译: 制备结晶形式A,B和纯结晶形式的埃洛替尼HCl的方法公开(公告)号:US20090131665A1
公开(公告)日:2009-05-21
申请号:US12229701
申请日:2008-08-25
IPC分类号: C07D239/94
CPC分类号: C07D239/94 , A61K9/0048 , A61K9/2013 , A61K9/2018 , A61K9/2054
摘要: The invention provides processes for preparing crystalline Forms A, B and pure crystalline Form A of Erlotinib hydrochloride.
摘要翻译: 本发明提供了制备盐酸埃罗替尼的结晶形式A,B和纯结晶形式A的方法。
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公开(公告)号:US20090118297A1
公开(公告)日:2009-05-07
申请号:US12257338
申请日:2008-10-23
申请人: Ondrej SIMO , Jiri Filipcik , Alexandr Martaus , Alexandr Jegorov , Ales Gavenda , Judith Aronhime , Pavel Vraspir , Tamas Koltai , Jiri Faustmann , Roman Gabriel
发明人: Ondrej SIMO , Jiri Filipcik , Alexandr Martaus , Alexandr Jegorov , Ales Gavenda , Judith Aronhime , Pavel Vraspir , Tamas Koltai , Jiri Faustmann , Roman Gabriel
IPC分类号: A61K31/506 , C07D417/14
CPC分类号: C07D417/12
摘要: Provided is dasatinib, solvates thereof and their crystalline forms, methods for their preparation, and pharmaceutical compositions thereof.
摘要翻译: 提供达沙替尼,其溶剂合物及其结晶形式,其制备方法及其药物组合物。
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5.Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form alpha 有权
标题翻译: 甲磺酸伊马替尼的多晶型形式以及制备新型结晶形式以及无定型和形成α的方法公开(公告)号:US20090264438A1
公开(公告)日:2009-10-22
申请号:US12148492
申请日:2008-04-17
IPC分类号: C07D401/14 , A61K31/496
CPC分类号: C07D401/04
摘要: Solvates and crystalline forms of imatinib mesylate are described. Further, methods for preparing such solvates and crystalline forms of imatinib mesylate are described.
摘要翻译: 描述了甲磺酸伊马替尼的溶剂合物和结晶形式。 此外,描述了制备这种溶剂化物的方法和甲磺酸伊马替尼的结晶形式。
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6.Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form alpha 有权
标题翻译: 甲磺酸伊马替尼的多晶型形式以及制备新型结晶形式以及无定型和形成α的方法公开(公告)号:US20080090833A1
公开(公告)日:2008-04-17
申请号:US11796573
申请日:2007-04-27
IPC分类号: A61K31/497 , C07D239/20
CPC分类号: C07D401/04
摘要: Solvates and crystalline forms of imatinib mesylate are described. Further, methods for preparing such solvates and crystalline forms of imatinib mesylate are described.
摘要翻译: 描述了甲磺酸伊马替尼的溶剂合物和结晶形式。 此外,描述了制备这种溶剂化物的方法和甲磺酸伊马替尼的结晶形式。
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7.
公开(公告)号:US08148353B2
公开(公告)日:2012-04-03
申请号:US12462782
申请日:2009-08-06
申请人: Peter Lindsay MacDonald , Pierluigi Rossetto , Adrienne Kovacsne-Mezei , Roman Gabriel , Alexandr Jegorov , Jiri Faustmann
发明人: Peter Lindsay MacDonald , Pierluigi Rossetto , Adrienne Kovacsne-Mezei , Roman Gabriel , Alexandr Jegorov , Jiri Faustmann
CPC分类号: C07J31/006
摘要: Provided are polymorphs of fluticasone furoate and processes for preparation thereof.
摘要翻译: 提供糠酸氟替卡松的多晶型物及其制备方法。
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8.
公开(公告)号:US20100130458A1
公开(公告)日:2010-05-27
申请号:US12462782
申请日:2009-08-06
申请人: Peter Lindsay Macdonald , Pierluigi Rossetto , Adrienne Kovacsne-Mezei , Roman Gabriel , Alexandr Jegorov , Jiri Faustmann
发明人: Peter Lindsay Macdonald , Pierluigi Rossetto , Adrienne Kovacsne-Mezei , Roman Gabriel , Alexandr Jegorov , Jiri Faustmann
IPC分类号: A61K31/58 , C07J31/00 , A61P11/06 , A61P17/00 , A61P17/06 , A61P11/02 , C07D239/04 , C07D319/00 , C07D233/02
CPC分类号: C07J31/006
摘要: Provided are polymorphs of fluticasone furoate and processes for preparation thereof.
摘要翻译: 提供糠酸氟替卡松的多晶型物及其制备方法。
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公开(公告)号:US20080262223A1
公开(公告)日:2008-10-23
申请号:US11596758
申请日:2006-03-17
IPC分类号: C07D223/16
CPC分类号: C07D491/06
摘要: The subject matter of present invention relates to the process for isolation and purification of galanthamine and its derivatives produced by numerous plants.
摘要翻译: 本发明的主题涉及由许多植物产生的雪花胺及其衍生物的分离和纯化方法。
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10.
公开(公告)号:US20080254520A1
公开(公告)日:2008-10-16
申请号:US12082484
申请日:2008-04-11
申请人: Eva Gulyas , Gabor Balogh , Janos Erdei , Laszlo Toth , Boglarka Szikszai , Alexandr Jegorov , Jiri Faustmann
发明人: Eva Gulyas , Gabor Balogh , Janos Erdei , Laszlo Toth , Boglarka Szikszai , Alexandr Jegorov , Jiri Faustmann
IPC分类号: C12P17/16 , C07D307/54 , G01N33/50 , C07D413/12 , C12P17/04
CPC分类号: C12P17/04 , C07D307/88 , Y10T436/142222
摘要: The present invention relates to methods for reducing impurities of mycophenolic acid during fermentation by controlling the level of carbon source during fermentation of mycophenolic acid and for the isolation and use as a standard marker of the impurity homo-mycophenolic acid.
摘要翻译: 本发明涉及在发酵过程中通过控制霉酚酸发酵过程中碳源的含量以及分离和用作杂质均霉酚酸的标准标记来减少发酵过程中霉酚酸的杂质的方法。
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