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1.发明申请METHOD, APPARATUS, COMPUTER-READABLE MEDIUM AND USE FOR PHARMACOKINETIC MODELING 审中-公开方法，装置，计算机可读介质和用于药物动力学建模公开(公告)号：US20100201686A1
公开(公告)日：2010-08-12
申请号：US12671244
申请日：2007-08-03
申请人： Timo Paulus , Alexander Fischer , Lothar Spies
发明人： Timo Paulus , Alexander Fischer , Lothar Spies
IPC分类号： G06T17/00
CPC分类号： H04L51/14
摘要： Methods and systems for interworking in messaging systems are described. An event store can be accessible by different dispatchers associated with different message servers. The dispatchers may be co-located with the event store or non co-located with the event store.
摘要翻译： 描述了消息系统中互通的方法和系统。 可以通过与不同消息服务器相关联的不同调度器访问事件存储。 调度员可以与事件存储共同定位，也可以与事件存储不同。
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2.发明申请Knowledge-Based Input Region of Interest Definition for Pharmacokinetic Modeling 失效基于知识的输入区域药代动力学建模的兴趣定义公开(公告)号：US20080228686A1
公开(公告)日：2008-09-18
申请号：US12067481
申请日：2006-09-13
申请人： Alexander Fischer , Lothar Spies
发明人： Alexander Fischer , Lothar Spies
IPC分类号： G06N5/02
CPC分类号： G06T7/0012 , A61B5/055 , G01R33/5608 , G06K9/3233 , G06K2209/05 , G06T7/11 , G06T2207/30004
摘要： The present invention provides a system, apparatus, and method that are based on a priori knowledge of the shape of the input function for defining an input region-if-interest (ROI) in pharmacokinetic modeling. Kinetic parameter estimation requires knowledge of tracer input activity and the present invention provides an automatic way to define an ROI for estimation of an input function that takes into account a priori knowledge of the shape of the input function based on an administered dose. As a result of the application of the present invention to existing imaging analysis systems, there is a reduction in the amount of manual interaction needed and operator dependence is thereby reduced in the evaluation of dynamic procedures.
摘要翻译： 本发明提供一种系统，装置和方法，其基于用于在药代动力学建模中定义输入区域 - 如果兴趣（ROI）的输入函数的形状的先验知识。 动力学参数估计需要了解示踪剂输入活动的知识，并且本发明提供了一种自动方式来定义用于估计输入功能的ROI，其基于施用的剂量考虑到输入功能的形状的先验知识。 作为将本发明应用于现有成像分析系统的结果，在动态过程的评估中减少了所需的手动交互量，从而减少了操作者依赖性。
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3.发明授权Knowledge-based input region of interest definition for pharmacokinetic modeling 失效基于知识的输入兴趣定义为药代动力学建模公开(公告)号：US08103609B2
公开(公告)日：2012-01-24
申请号：US12067481
申请日：2006-09-13
申请人： Alexander Fischer , Lothar Spies
发明人： Alexander Fischer , Lothar Spies
CPC分类号： G06T7/0012 , A61B5/055 , G01R33/5608 , G06K9/3233 , G06K2209/05 , G06T7/11 , G06T2207/30004
摘要： A system, apparatus, and method are based on a priori knowledge of the shape of the input function for defining an input region-if-interest (ROI) in pharmacokinetic modeling. Kinetic parameter estimation requires knowledge of tracer input activity and the present invention provides an automatic way to define an ROI for estimation of an input function that takes into account a priori knowledge of the shape of the input function based on an administered dose.
摘要翻译： 系统，装置和方法基于用于在药代动力学建模中定义输入区域 - 如果兴趣（ROI）的输入函数的形状的先验知识。 动力学参数估计需要了解示踪剂输入活动的知识，并且本发明提供了一种自动方式来定义用于估计输入功能的ROI，其基于施用的剂量考虑到输入功能的形状的先验知识。
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公开(公告)号：US08064672B2
公开(公告)日：2011-11-22
申请号：US12088088
申请日：2006-09-15
IPC分类号： G06K9/00
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译： 成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。 重组处理器（40）将获取的数据周期性地存储到直方图（42）中。 变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。 停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。
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公开(公告)号：US20090208075A1
公开(公告)日：2009-08-20
申请号：US12300341
申请日：2007-05-01
申请人： Alexander Fischer , Lothar Spies , Carsten Meyer
发明人： Alexander Fischer , Lothar Spies , Carsten Meyer
CPC分类号： G06T7/11 , G06K9/6218 , G06T2207/10104 , G06T2207/20016 , G06T2207/20021 , G06T2207/30096
摘要： A method for use in functional medical imaging includes adaptively partitioning functional imaging data as a function of a spatially varying error model. The functional image data is partitioned according to an optimization strategy. The data may be visualized or used to plan a course of treatment. In one implementation, the image data is partitioned so as to vary its spatial resolution. In another, the number of clusters is varied based on the error model.
摘要翻译： 用于功能医学成像的方法包括根据空间变化的误差模型自适应地划分功能成像数据。 功能图像数据根据优化策略进行分区。 数据可以被可视化或用于计划治疗过程。 在一个实现中，图像数据被分割以改变其空间分辨率。 另一方面，群集的数量根据误差模型而变化。
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公开(公告)号：US20090171183A1
公开(公告)日：2009-07-02
申请号：US12088088
申请日：2006-09-15
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译： 成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。 重组处理器（40）将获取的数据周期性地存储到直方图（42）中。 变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。 停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。
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公开(公告)号：US08170308B2
公开(公告)日：2012-05-01
申请号：US12300341
申请日：2007-05-01
申请人： Alexander Fischer , Lothar Spies , Carsten Meyer
发明人： Alexander Fischer , Lothar Spies , Carsten Meyer
IPC分类号： G06K9/00
CPC分类号： G06T7/11 , G06K9/6218 , G06T2207/10104 , G06T2207/20016 , G06T2207/20021 , G06T2207/30096
摘要： A method for use in functional medical imaging includes adaptively partitioning functional imaging data as a function of a spatially varying error model. The functional image data is partitioned according to an optimization strategy. The data may be visualized or used to plan a course of treatment. In one implementation, the image data is partitioned so as to vary its spatial resolution. In another, the number of clusters is varied based on the error model.
摘要翻译： 用于功能医学成像的方法包括根据空间变化的误差模型自适应地划分功能成像数据。 功能图像数据根据优化策略进行分区。 数据可以被可视化或用于计划治疗过程。 在一个实现中，图像数据被分割以改变其空间分辨率。 另一方面，群集的数量根据误差模型而变化。
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公开(公告)号：US20090264728A1
公开(公告)日：2009-10-22
申请号：US12375430
申请日：2007-07-23
申请人： Alexander Fischer , Lothar Spies
发明人： Alexander Fischer , Lothar Spies
摘要： A therapy system (100) includes an imager (102), a therapy planner (104), and a therapy device (106). The therapy planner (104) includes a therapy prescription apparatus (118) which calculates a desired therapy (D) to be applied to a human patient or other subject. The therapy prescription system (118) uses a pathology model (122) and a patient-specific biological parameter history (124) to optimize the applied therapy.
摘要翻译： 治疗系统（100）包括成像器（102），治疗计划器（104）和治疗装置（106）。 治疗计划器（104）包括治疗处方设备（118），其计算要应用于人类患者或其他受试者的期望治疗（D）。 治疗处方系统（118）使用病理模型（122）和患者特异性生物参数历史（124）来优化应用治疗。
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公开(公告)号：US20150169145A1
公开(公告)日：2015-06-18
申请号：US13540414
申请日：2012-07-02
申请人： Raj Krishnan , Ryan Kelly , Daniel Rocha , Harvey C. Jones , Jeremy Silber , Hannah Allison Johnston , Russell Yanofsky , Yegnaswamy Ramakrishnan Sermadevi , Alexander Fischer
发明人： Raj Krishnan , Ryan Kelly , Daniel Rocha , Harvey C. Jones , Jeremy Silber , Hannah Allison Johnston , Russell Yanofsky , Yegnaswamy Ramakrishnan Sermadevi , Alexander Fischer
IPC分类号： G06F3/0482 , G06F17/30 , G06F3/0484
CPC分类号： G06F17/30277 , G06F17/30864 , G06F17/30991
摘要： A method and system for providing user-navigable search results returns a resource representation for a resource, such as a web site or other Internet accessible object. The resource representation may be navigable by a user in a manner mirroring navigation of the resource. The resource representation may include a plurality of indicators representing menu links selected from resource links associated with the resource. Selection of an indicator may cause content associated with the indicator, such as resource links and related snippets, to be displayed. A hierarchical arrangement of elements in the resource representation may correspond to a hierarchical arrangement of navigable content in the resource.
摘要翻译： 用于提供用户导航搜索结果的方法和系统返回资源（例如网站或其他因特网可访问对象）的资源表示。 资源表示可以由用户以能够反映资源导航的方式导航。 资源表示可以包括表示从与资源相关联的资源链路中选择的菜单链接的多个指示符。 指示符的选择可能导致显示与指示符相关联的内容，例如资源链接和相关片段。 资源表示中的元素的分层布置可以对应于资源中的可导航内容的分层布置。
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10.发明授权公开(公告)号：US09047539B2
公开(公告)日：2015-06-02
申请号：US12195669
申请日：2008-08-21
申请人： Uma S. Ranjan , Alexander Fischer , Andrew J. Buckler , Shuping Xie , Shivakumar Kunigal Ramaswamy
发明人： Uma S. Ranjan , Alexander Fischer , Andrew J. Buckler , Shuping Xie , Shivakumar Kunigal Ramaswamy
CPC分类号： G06K9/6284 , G06F19/00 , G06F19/321 , G06Q50/24
摘要： A medical information processing and storage system includes a medical images database storing medical images and metadata relevant to the medical images. A processor is configured to perform post-acquisition image processing on medical images. A medical images archiver is configured to store a medical image in the medical images database after the medical image has been processed by the processor. The medical images archiver stores the medical image in the database with processing-descriptive metadata that is descriptive of the post-acquisition image processing performed on the medical image by the processor.
摘要翻译： 医疗信息处理和存储系统包括存储与医学图像相关的医学图像和元数据的医学图像数据库。 处理器被配置为对医学图像执行采集后图像处理。 医疗图像存档器被配置为在处理器处理了医学图像之后，将医学图像存储在医学图像数据库中。 医学图像存档器将医学图像存储在数据库中，其处理描述性元数据描述了由处理器对医学图像执行的采集后图像处理。
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