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公开(公告)号：US20230044430A1
公开(公告)日：2023-02-09
申请号：US17808964
申请日：2022-06-24
IPC分类号： A61K47/68 , A61P35/00 , A61K31/216 , A61K31/215 , A61K31/222
摘要： The present disclosure provides methods for site-selectively crosslinking payloads to antibodies and other proteins. This can be accomplished using traceless affinity labels designed to label target proteins with bio-orthogonally reactive entities (ORE) using the compositions and methods described herein.
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公开(公告)号：US20200095275A1
公开(公告)日：2020-03-26
申请号：US16403971
申请日：2019-05-06
IPC分类号： C07K1/13 , A61K47/65 , A61K47/60 , A61K47/62 , A61K31/55 , C07K1/06 , C07K1/08 , C07K16/32 , G01N33/532 , A61K47/68
摘要： The present disclosure relates to site-selective labeling compounds, and methods of using such compounds.
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公开(公告)号：US10329321B2
公开(公告)日：2019-06-25
申请号：US15427678
申请日：2017-02-08
IPC分类号： C07K1/13 , A61K31/55 , C07K1/06 , C07K1/08 , C07K16/32 , G01N33/532 , A61K47/65 , A61K47/60 , A61K47/62 , A61K47/68
摘要： The present disclosure relates to site-selective labeling compounds, and methods of using such compounds.
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公开(公告)号：US20170275331A1
公开(公告)日：2017-09-28
申请号：US15427678
申请日：2017-02-08
CPC分类号： C07K1/13 , A61K31/55 , A61K47/60 , A61K47/62 , A61K47/65 , C07K1/062 , C07K1/084 , C07K16/32 , C07K2317/24 , G01N33/532
摘要： The present disclosure relates to site-selective labeling compounds, and methods of using such compounds.
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