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1.
公开(公告)号:US08369600B2
公开(公告)日:2013-02-05
申请号:US12055038
申请日:2008-03-25
CPC分类号: G01N1/312 , G01N2001/368 , G01N2800/60
摘要: The present techniques provide systems and methods for registering images of tissue spots on a tissue microarray (TMA). In studies involving multiple biomarkers being studied on the same TMA, the TMA slide is removed from the microscope, stained, and then imaged, often multiple times. The present techniques relate to validation of the registration of the acquired images of the same TMA. An automatic approach to register the images and detect registration failures as provided herein may enhance the rapid analysis of the tissues. Artifacts such as tissue folding and tissue loss are also determined automatically.
摘要翻译: 本技术提供了用于在组织微阵列(TMA)上记录组织斑点的图像的系统和方法。 在涉及在相同TMA上研究的多种生物标志物的研究中,将TMA载玻片从显微镜中除去,染色,然后成像,通常多次。 本技术涉及对相同TMA的所获取的图像的注册的验证。 如本文所提供的注册图像和检测登记失败的自动方法可以增强组织的快速分析。 人工制品如组织折叠和组织损失也自动确定。
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公开(公告)号:US08880351B2
公开(公告)日:2014-11-04
申请号:US12055121
申请日:2008-03-25
CPC分类号: G01N21/6452 , G06T7/30 , G06T2207/30072
摘要: The present techniques include methods and systems for finding correspondences between tissue spots in tissue microarray serial sections belonging to the same recipient block. The present techniques may also be used to relate individual tissue cores to clinical information. Using either a whole slide image or the relative x-y coordinates of the tissue spots on the slide, individual tissue spots in different tissue microarrays may be linked to one another and their clinical information.
摘要翻译: 本技术包括用于在属于相同受体块的组织微阵列序列区段中发现组织斑点之间的对应关系的方法和系统。 本技术还可以用于将个体组织核心与临床信息相关联。 使用整个幻灯片图像或幻灯片上组织斑点的相对x-y坐标,不同组织微阵列中的各个组织斑点可以彼此连接并且其临床信息。
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公开(公告)号:US20090247416A1
公开(公告)日:2009-10-01
申请号:US12055121
申请日:2008-03-25
CPC分类号: G01N21/6452 , G06T7/30 , G06T2207/30072
摘要: The present techniques include methods and systems for finding correspondences between tissue spots in tissue microarray serial sections belonging to the same recipient block. The present techniques may also be used to relate individual tissue cores to clinical information. Using either a whole slide image or the relative x-y coordinates of the tissue spots on the slide, individual tissue spots in different tissue microarrays may be linked to one another and their clinical information.
摘要翻译: 本技术包括用于在属于相同受体块的组织微阵列序列区段中发现组织斑点之间的对应关系的方法和系统。 本技术还可以用于将个体组织核心与临床信息相关联。 使用整个幻灯片图像或幻灯片上组织斑点的相对x-y坐标,不同组织微阵列中的各个组织斑点可以彼此连接并且其临床信息。
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4.
公开(公告)号:US20090245610A1
公开(公告)日:2009-10-01
申请号:US12055038
申请日:2008-03-25
IPC分类号: G01N33/52
CPC分类号: G01N1/312 , G01N2001/368 , G01N2800/60
摘要: The present techniques provide systems and methods for registering images of tissue spots on a tissue microarray (TMA). In studies involving multiple biomarkers being studied on the same TMA, the TMA slide is removed from the microscope, stained, and then imaged, often multiple times. The present techniques relate to validation of the registration of the acquired images of the same TMA. An automatic approach to register the images and detect registration failures as provided herein may enhance the rapid analysis of the tissues. Artifacts such as tissue folding and tissue loss are also determined automatically.
摘要翻译: 本技术提供了用于在组织微阵列(TMA)上记录组织斑点的图像的系统和方法。 在涉及在相同TMA上研究的多种生物标志物的研究中,将TMA载玻片从显微镜中除去,染色,然后成像,通常多次。 本技术涉及对相同TMA的所获取的图像的注册的验证。 如本文所提供的注册图像和检测登记失败的自动方法可以增强组织的快速分析。 人工制品如组织折叠和组织损失也自动确定。
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