公开(公告)号：US10975099B2

公开(公告)日：2021-04-13

申请号：US16674040

申请日：2019-11-05

申请人： Alkermes Pharma Ireland Limited

发明人： Brian M. Aquila ,  Hoan Huynh ,  Lewis D. Pennington ,  Ingo Mugge ,  Baudouin Gerard ,  Markus Haeberlein ,  Roman A. Valiulin ,  Julius F. Remenar ,  Demetri Theodore Moustakas ,  Thomas Andrew Wynn ,  Todd Bosanac

IPC分类号： C07D519/00 ,  C07D489/00 ,  A61K31/485 ,  A61K9/00 ,  A61P25/30

摘要： The present invention provides compounds useful for the treatment of opioid dependence, alcohol dependence, alcohol use disorder, or the prevention of relapse to opioid dependence in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

公开(公告)号：US10807995B2

公开(公告)日：2020-10-20

申请号：US16508697

申请日：2019-07-11

申请人： Alkermes Pharma Ireland Limited

发明人： Brian M. Aquila ,  Hoan Huynh ,  Lewis D. Pennington ,  Ingo Mugge ,  Baudouin Gerard ,  Markus Haeberlein ,  Roman A. Valiulin ,  Julius F. Remenar ,  Demetri T. Moustakas ,  Thomas Andrew Wynn ,  Todd Bosanac

IPC分类号： C07D519/00 ,  A61K9/00

摘要： The present invention provides compounds useful for the treatment of opioid dependence, alcohol dependence, alcohol use disorder, or the prevention of relapse to opioid dependence in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

公开(公告)号：US20200016151A1

公开(公告)日：2020-01-16

申请号：US16508703

申请日：2019-07-11

申请人： Alkermes Pharma Ireland Limited

发明人： Brian M. Aquila ,  Hoan Huynh ,  Lewis D. Pennington ,  Ingo Mugge ,  Baudouin Gerard ,  Markus Haeberlein ,  Roman A. Valiulin ,  Julius F. Remenar ,  Demetri T. Moustakas ,  Thomas Andrew Wynn ,  Todd Bosanac

IPC分类号： A61K31/485 ,  A61K9/00 ,  A61K47/55 ,  A61K47/54

摘要： The present invention provides compounds useful for the treatment of opioid dependence, alcohol dependence, alcohol use disorder, or the prevention of relapse to opioid dependence in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

公开(公告)号：US20200017529A1

公开(公告)日：2020-01-16

申请号：US16508697

申请日：2019-07-11

申请人： Alkermes Pharma Ireland Limited

发明人： Brian M. Aquila ,  Hoan Huynh ,  Lewis D. Pennington ,  Ingo Mugge ,  Baudouin Gerard ,  Markus Haeberlein ,  Roman A. Valiulin ,  Julius F. Remenar ,  Demetri T. Moustakas ,  Thomas Andrew Wynn ,  Todd Bosanac

IPC分类号： C07D519/00 ,  A61K9/00

摘要： The present invention provides compounds useful for the treatment of opioid dependence, alcohol dependence, alcohol use disorder, or the prevention of relapse to opioid dependence in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

公开(公告)号：US10799496B2

公开(公告)日：2020-10-13

申请号：US16508703

申请日：2019-07-11

申请人： Alkermes Pharma Ireland Limited

发明人： Brian M. Aquila ,  Hoan Huynh ,  Lewis D. Pennington ,  Ingo Mugge ,  Baudouin Gerard ,  Markus Haeberlein ,  Roman A. Valiulin ,  Julius F. Remenar ,  Demetri T. Moustakas ,  Thomas Andrew Wynn ,  Todd Bosanac

IPC分类号： A61K31/485 ,  A61K47/55 ,  A61K9/00 ,  A61K47/54

摘要： The present invention provides compounds useful for the treatment of opioid dependence, alcohol dependence, alcohol use disorder, or the prevention of relapse to opioid dependence in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.