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公开(公告)号：US20230405184A1
公开(公告)日：2023-12-21
申请号：US18238773
申请日：2023-08-28
Applicant: Allosource
Inventor： Megan Maccagnan , Cameron Mattson , Cole Watkins , Adrian C. Samaniego , William Maslanik
CPC classification number: A61L27/3608 , A61L27/3687 , A61B17/1635 , C12N5/0697 , A61L2430/38 , A61L27/3691
Abstract: Periosteum harvesting and processing systems and methods enable rapid, efficient, and repeatable harvesting of periosteum tissue from human long bones and processing of the tissue into individual fibers for use in strengthening surgical allograft products. One harvesting and processing method involves providing a human long bone, securing the long bone between two rotating live centers, scraping, using one of a plurality of harvesting tools selected from a harvesting and processing kit, periosteum tissue from the long bone, executing a first wash cycle comprising a hydrogen peroxide wash, executing a second wash cycle comprising an isopropyl alcohol wash, executing a third wash cycle comprising a phosphate buffered saline wash, compressing the periosteum tissue to remove excess fluid, cryofracturing the tissue until a desired fiber size is achieved, and separating the periosteum tissue into individual periosteum fibers having the desired fiber size. Other embodiments are also disclosed.
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公开(公告)号：US11806442B2
公开(公告)日：2023-11-07
申请号：US16571632
申请日：2019-09-16
Applicant: Allosource
Inventor： Megan Maccagnan , Cameron Mattson , Cole Watkins , Adrian C. Samaniego , William Maslanik
CPC classification number: A61L27/3608 , A61L27/3687 , A61L27/3691 , C12N5/0697 , A61B17/1635 , A61L2430/02 , A61L2430/38
Abstract: Periosteum harvesting and processing systems and methods enable rapid, efficient, and repeatable harvesting of periosteum tissue from human long bones and processing of the tissue into individual fibers for use in strengthening surgical allograft products. One harvesting and processing method involves providing a human long bone, securing the long bone between two rotating live centers, scraping, using one of a plurality of harvesting tools selected from a harvesting and processing kit, periosteum tissue from the long bone, executing a first wash cycle comprising a hydrogen peroxide wash, executing a second wash cycle comprising an isopropyl alcohol wash, executing a third wash cycle comprising a phosphate buffered saline wash, compressing the periosteum tissue to remove excess fluid, cryofracturing the tissue until a desired fiber size is achieved, and separating the periosteum tissue into individual periosteum fibers having the desired fiber size. Other embodiments are also disclosed.
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公开(公告)号：US20200086001A1
公开(公告)日：2020-03-19
申请号：US16571632
申请日：2019-09-16
Applicant: Allosource
Inventor： Megan Maccagnan , Cameron Mattson , Cole Watkins , Adrian C. Samaniego , William Maslanik
Abstract: Periosteum harvesting and processing systems and methods enable rapid, efficient, and repeatable harvesting of periosteum tissue from human long bones and processing of the tissue into individual fibers for use in strengthening surgical allograft products. One harvesting and processing method involves providing a human long bone, securing the long bone between two rotating live centers, scraping, using one of a plurality of harvesting tools selected from a harvesting and processing kit, periosteum tissue from the long bone, executing a first wash cycle comprising a hydrogen peroxide wash, executing a second wash cycle comprising an isopropyl alcohol wash, executing a third wash cycle comprising a phosphate buffered saline wash, compressing the periosteum tissue to remove excess fluid, cryofracturing the tissue until a desired fiber size is achieved, and separating the periosteum tissue into individual periosteum fibers having the desired fiber size. Other embodiments are also disclosed.
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