公开(公告)号：US20230373955A1

公开(公告)日：2023-11-23

申请号：US18359467

申请日：2023-07-26

Applicant: Amgen Inc.

Inventor： Sebastien CAILLE ,  Kyle QUASDORF ,  Philipp C. ROOSEN ,  Xianqing SHI ,  Andrew COSBIE ,  Fang WANG ,  Zufan WU ,  Archana NEERGUNDA ,  Bin Peter QUAN ,  Lianxiu GUAN

IPC: C07D401/12 ,  C07D241/04

CPC classification number: C07D401/12 ,  C07D241/04

Abstract: Provided herein is a synthesis for omecamtiv mecarbil dihydrochloride hydrate and various intermediates. (1)

公开(公告)号：US20250163023A1

公开(公告)日：2025-05-22

申请号：US19029945

申请日：2025-01-17

Applicant: Amgen Inc.

Inventor： Sebastien CAILLE ,  Kyle QUASDORF ,  Philipp C. ROOSEN ,  Xianqing SHI ,  Andrew COSBIE ,  Fang WANG ,  Zufan WU ,  Archana NEERGUNDA ,  Bin Peter QUAN ,  Lianxiu GUAN

IPC: C07D401/12 ,  C07D241/04

Abstract: Provided herein is a synthesis for omecamtiv mecarbil dihydrochloride hydrate and various intermediates.