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公开(公告)号：US5672167A
公开(公告)日：1997-09-30
申请号：US227968
申请日：1994-04-15
CPC分类号： A61M5/1483 , A61M2005/14513 , A61M5/14248 , Y10S977/956
摘要： A portable osmotic pump, having two pouches (4,3) in pressure-transmitting relationship, the first (4) containing a pumped fluid, such as infusate (5), and the second (3), a driving fluid (36). The driving fluid is created and pressurized by activation of an osmotic pump, and the rate of infusion is controlled by a semipermeable membrane (10). Activation can be by rupturing a seal (11) or by opening a closed tube (58) to permit permeant (2) to contact the semipermeable membrane. Pulses of the pumped fluid can be achieved by delivery pulses of the permeant to the second pouch. The pouches can be designed to resist collapse of the first pouch by external forces on the pumped liquid, such as gravity, movement of the first pouch and negative pressures applied to the pumped liquid. The infusate pouch is manufactured separately and can be stored apart from the rest of the system.
摘要翻译： 一种具有压力传递关系的两个袋（4,3）的便携式渗透泵，所述第一（4）包含诸如输液（5）和第二（3）的泵送流体，驱动流体（36）。 通过激活渗透泵来产生和加压驱动流体，并且输注速率由半透膜（10）控制。 活化可以是破裂密封件（11）或打开封闭管（58）以允许渗透物（2）接触半透膜。 泵送流体的脉冲可以通过渗透物向第二袋的输送脉冲来实现。 小袋可以被设计成抵抗泵送液体上的外力，例如重力，第一袋的运动和施加到泵送的液体上的负压，使第一袋的崩溃。 输液袋分开制造，可以与系统的其余部分分开储存。
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公开(公告)号：US5492534A
公开(公告)日：1996-02-20
申请号：US246641
申请日：1994-05-20
CPC分类号： A61M5/148 , A61M5/1483 , A61M2005/14204 , A61M2005/14513 , A61M5/14248 , A61M5/16881
摘要： A portable pump, useful for medical and non-medical uses, has two pouches (3, 4) in pressure transmitting relationship, the first (4) containing an infusate (5) and the second (3), a driving medium (2). The driving medium is pressurized in any of a variety of ways, including activation of osmotic pump, electrochemical reaction (19), release of pressurized fluid or gas (21, 23) or mechanical means (24). The rate of infusion is controlled by a rate controller (18). The infusate pouch is separately manufactured and can be stored apart of the rest of the system. Pulses of pumped fluid can also be delivered according to one aspect of the invention (18, 40).
摘要翻译： 用于医疗和非医疗用途的便携式泵具有压力传递关系的两个袋（3,4），第一（4）包含输注（5）和第二（3），驱动介质（2） 。 驱动介质以各种方式中的任一种加压，包括渗透泵的活化，电化学反应（19），加压流体或气体的释放（21,23）或机械装置（24）。 输注速率由速率控制器（18）控制。 输液袋是分开制造的，可以在系统的其余部分分开存放。 泵送流体的脉冲也可以根据本发明的一个方面进行输送（18,40）。
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公开(公告)号：US5169390A
公开(公告)日：1992-12-08
申请号：US526129
申请日：1990-05-21
申请人： Amulya L. Athayde , Rolf A. Faste
发明人： Amulya L. Athayde , Rolf A. Faste
CPC分类号： A61M5/1483 , A61M5/145 , A61M2005/14513 , A61M5/14244 , Y10S128/12 , Y10S977/956
摘要： A portable infusion device assembly where the drug is contained in a separate or separatable pouch in pressure transmitting relationship with a driving medium. The driving medium is pressurized by activation of osmotic pump, and the rate of delivery of the drug is regulated by a rate controlling means. Manufacture and sterilization of the infusate containing pouch separately from the other components of the systems to facilitates construction of sterile infusion pumps and provides an additional measure of safety.
摘要翻译： 一种便携式输注装置组件，其中药物被容纳在与驱动介质压力传递关系的单独的或可分离的袋中。 驱动介质通过渗透泵的活化而被加压，并且药物的传送速率由速率控制装置调节。 将含有输入物的袋子与系统的其他部件分开制造和灭菌，以便于建立无菌输液泵并提供额外的安全措施。
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公开(公告)号：US5318540A
公开(公告)日：1994-06-07
申请号：US957446
申请日：1992-10-06
申请人： Amulya L. Athayde , Rolf A. Faste
发明人： Amulya L. Athayde , Rolf A. Faste
CPC分类号： A61M5/1483 , A61M5/148 , A61M2005/14204 , A61M2005/14513 , A61M5/14248
摘要： A portable infusion device assembly, having two pouches in pressure transmitting relationship, the first containing infusate and the second, a driving medium. The driving medium is pressurized by activation of osmotic pump, electrochemical reaction, release of pressurized fluid or gas or mechanical means and the rate of infusion is controlled by a rate controlling means. The infusate pouch is separately manufactured and can be stored apart of the rest of the system.
摘要翻译： 具有压力传递关系的两个袋的便携式输注装置组件，第一容纳输液管和第二容器，驱动介质。 驱动介质通过渗透泵的激活，电化学反应，加压流体或气体的释放或机械装置的压力被加压，并且输注速率由速率控制装置控制。 输液袋是分开制造的，可以在系统的其余部分分开存放。
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公开(公告)号：US5257987A
公开(公告)日：1993-11-02
申请号：US526120
申请日：1990-05-21
申请人： Amulya L. Athayde , Rolf A. Faste
发明人： Amulya L. Athayde , Rolf A. Faste
CPC分类号： A61M5/145 , A61M2005/14513 , A61M5/14248 , Y10S128/12 , Y10S977/956
摘要： A portable osmotic infusion device assembly, having two pouches in pressure transmitting relationship, the first containing infusate and the second, a driving fluid. The driving fluid is created and pressurized by activation of an osmotic pump, and the rate of infusion is controlled by a rate-controlling means. The infusate pouch is manufactured separately and can be stored apart from the rest of the system.
摘要翻译： 一种具有压力传递关系的两个袋的便携式渗透输注装置组件，所述第一容纳输液器和第二容器包括驱动流体。 通过激活渗透泵来产生和加压驱动流体，并且通过速率控制装置控制输注速率。 输液袋分开制造，可以与系统的其余部分分开储存。
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公开(公告)号：US4428369A
公开(公告)日：1984-01-31
申请号：US284674
申请日：1981-07-20
CPC分类号： A61F5/0123
摘要： A corrective and protective knee brace wherein the upper and lower portions of the brace are connected together in such a manner that the flexing movement of the brace closely simulates the rolling and sliding movement of the human knee. The simulated knee movement is accomplished in the brace by a novel roller and inclined plane mechanism which coacts with flexible interconnecting cables. The upper portion of the knee brace includes a pair of pressure pads for engagement with opposite sides of the wearer's leg above the knee, and the lower portion of the brace includes a pair of pressure pads for engagement with opposite sides of the wearer's leg below the knee. The brace is provided with a toggle mechanism that is operable after the brace has been positioned on the leg to cause the upper and lower pressure pads to exert inward pressure above and below the knee.
摘要翻译： 矫正和保护性膝盖支架，其中支架的上部和下部以这样的方式连接在一起，使得支架的弯曲运动紧密地模拟人膝盖的滚动和滑动运动。 模拟的膝盖运动通过与柔性互连电缆共同作用的新型辊和倾斜平面机构在支架中实现。 膝盖支架的上部包括一对压力垫，用于与膝盖上方的穿着者腿的相对侧接合，并且支架的下部包括一对压力垫，用于与穿着者的腿的相对侧配合， 膝盖。 支架设置有肘节机构，该肘节机构在支架已经被定位在腿上之后可操作，以使上压力垫和下压力垫在膝盖上方和下方施加向内的压力。
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公开(公告)号：US5135498A
公开(公告)日：1992-08-04
申请号：US503720
申请日：1990-04-02
申请人： Robert J. Kam , Rolf A. Faste , Anthony J. Castro
发明人： Robert J. Kam , Rolf A. Faste , Anthony J. Castro
IPC分类号： A61M5/148
CPC分类号： A61M5/1483 , A61M5/148 , Y10S128/12
摘要： A means for elimination or compression of trapped air spaces in osmotically powered pumps is disclosed in which the housing of the pump is constructed of movable portions so that movement of the said housing portions will force air out of the device or compress it to such an extent that activation of the pump will result in the minimum lag time between activation of the pump and infusate flow.
摘要翻译： 公开了一种用于消除或压缩渗透动力泵中的被捕获的空气空间的装置，其中泵的壳体由可移动部分构成，使得所述壳体部分的运动将迫使空气流出设备或将其压缩到这样的程度 泵的激活将导致泵的激活和输注流之间的最小滞后时间。
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公开(公告)号：US4898582A
公开(公告)日：1990-02-06
申请号：US230620
申请日：1988-08-09
申请人： Rolf A. Faste
发明人： Rolf A. Faste
CPC分类号： A61M5/145 , A61M2005/14513 , A61M5/14248 , Y10S128/12
摘要： A portable infusion device assembly, having two side-by-side compartments, the first containing the drug or agent to be infused and an osmotic pump, and the second containing the driving liquid for the pump. The two chambers are separated during storage by a barrier. When the barrier is ruptured, the driving fluid is carried by means of a wick to the osmotic pump. The drug is then forced out of the device by the pressure developed by the osmotic pump. The assembly is characterized by a very flat profile, and is light, comfortable, and inconspicuous in use.
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