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    Compounds useful in therapy
    6.
    发明申请
    Compounds useful in therapy 失效
    化合物可用于治疗

    公开(公告)号：US20060241125A1

    公开(公告)日：2006-10-26

    申请号：US11408286

    申请日：2006-04-18

    申请人： Paul Bradley ,  Kevin Dack ,  Ian Marsh

    发明人： Paul Bradley ,  Kevin Dack ,  Ian Marsh

    IPC分类号： A61K31/506 ,  A61K31/4152 ,  C07D403/02

    CPC分类号： C07D231/28 ,  C07D231/18 ,  C07D401/04 ,  C07D401/06 ,  C07D403/04 ,  C07D403/06 ,  C07D413/06 ,  C07D417/06

    摘要： Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein: R1 represents H, C1-6-alkyl, C1-6alkyloxy, C3-8cycloalkyl, or halo; R2 represents H, C1-6alkyl (optionally substituted by R3), phenyl (optionally substituted by CN), or Het; R3 represents OH, CN, Het, —R4—C1-6alkyl, or CONR5R6; R4 represents —CO2—, or —O—; R5 and R6 independently represent H, C1-6alkyl (optionally substituted by OR7) or C3-8cycloalkyl; R7 represents H or C1-6alkyl; Het represents a five or six membered aromatic heterocyclic group containing (i) from one to four nitrogen heteroatom(s) or (ii) one or two nitrogen heteroatom(s) and one oxygen or one sulphur heteroatom or (iii) one or two oxygen or sulphur heteroatom(s), said heterocyclic group being optionally substituted by one or more groups selected from CN and C1-6 alkyl; R8 represents C1-6alkyl, C1-6alkyloxy, C3-8cycloalkyl, or halo; R9 and R10 independently represent H, C1-6alkyl, C1-6alkyloxy, CN, CF3 or halo; may be useful for treating endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.

    摘要翻译： 式（I）化合物或其药学上可接受的衍生物，其中：R 1表示H，C 1-6烷基，C 1-6烷基， 烷氧基，C 3-8环烷基或卤素; R 2表示H，C 1-6烷基（任选被R 3 O 3取代），苯基（任选被CN取代）或Het; R 3表示OH，CN，Het，-R 4 -C 1-6烷基或CONR 5 R 6; R 4表示-CO 2 - 或-O-; R 5和R 6独立地表示H，C 1-6烷基（任选被OR 7取代）或 C 3-8环烷基; R 7表示H或C 1-6烷基; Het表示含有（i）1-4个氮杂原子或（ii）一个或两个氮杂原子和一个氧或一个硫杂原子的五元或六元芳族杂环基，或（iii）一个或两个氧 或硫杂原子，所述杂环基团任选被一个或多个选自CN和C 1-6烷基的基团取代; R 8表示C 1-6烷基，C 1-6烷氧基，C 3-8环烷基，或 光环; R 9和R 10独立地代表H，C 1-6烷基，C 1-6烷氧基，CN CF 3或卤素; 可能有助于治疗子宫内膜异位症，子宫肌瘤（平滑肌瘤），月经过多，子宫腺肌症，原发性和继发性痛经（包括性交疼痛，dyschexia和慢性盆腔疼痛症状）或慢性盆腔疼痛综合征。

    Vehicle Monitoring Device
    7.
    发明申请
    Vehicle Monitoring Device 审中-公开
    车辆监控装置

    公开(公告)号：US20160090040A1

    公开(公告)日：2016-03-31

    申请号：US14501341

    申请日：2014-09-30

    申请人： Ian Marsh

    发明人： Ian Marsh

    IPC分类号： B60R1/00 ,  H04N7/18

    CPC分类号： B60R1/00 ,  B60R2300/70 ,  H04N7/181

    摘要： A vehicle monitoring device provides comprehensive monitoring of areas both outside and within a vehicle. The device includes a plurality of operational controls positioned within an interior space of a vehicle. A monitor is positioned in the vehicle and operationally coupled to a processor such that the monitor displays images transmitted to the monitor from the processor. Each of a plurality of cameras is communicatively coupled to the processor. The cameras include exterior cameras outwardly directed for exterior images and an interior camera directed towards the interior space of the vehicle communicating an image of the operator of the vehicle to the processor. A transmitter is communicatively coupled to the processor wherein the image of the operator of the vehicle is transmitted to an extrinsic device relative to the vehicle.

    摘要翻译： 车辆监控装置对车辆外部和内部的区域进行综合监控。 该装置包括位于车辆的内部空间内的多个操作控制装置。 监视器位于车辆中并且可操作地耦合到处理器，使得监视器显示从处理器发送到监视器的图像。 多个摄像机中的每一个通信地耦合到处理器。 相机包括向外指向外部图像的外部照相机和指向车辆内部空间的内部照相机，其将车辆操作者的图像传送到处理器。 发射机通信地耦合到处理器，其中车辆的操作者的图像相对于车辆传输到外在装置。

    Airfoil
    8.
    外观设计
    Airfoil 有权
    翼型

    公开(公告)号：USD625672S1

    公开(公告)日：2010-10-19

    申请号：US29351091

    申请日：2009-11-30

    申请人： Ian Marsh

    设计人： Ian Marsh