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公开(公告)号:US20140357684A1
公开(公告)日:2014-12-04
申请号:US14464394
申请日:2014-08-20
申请人: Andrew KUNG , David ZIEGLER
发明人: Andrew KUNG , David ZIEGLER
IPC分类号: C07D417/02 , G01N33/50
CPC分类号: C12Q1/6886 , A61K31/437 , A61K31/496 , A61K31/506 , A61K45/06 , C07D417/02 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N33/5044 , G01N33/57407 , G01N33/57484 , G01N2800/52 , G01N2800/7028 , A61K2300/00
摘要: The present invention features a method for determining the prognosis for survival of a cancer patient. Methods for measuring the level of NOL3 expression in a cancer cell-containing sample from a patient, and comparing the level of NOL3 expression in the sample to a reference level of NOL3 expression are also included. A higher level of NOL3 relative to the reference level correlates with decreased survival of the patient, and an equivalent or lower level of NOL3 relative to the reference level correlates with increased survival of the patient.
摘要翻译: 本发明的特征在于确定癌症患者的存活预后的方法。 还包括用于测量来自患者的含癌细胞的样品中的NOL3表达水平以及将样品中NOL3表达水平与NOL3表达的参考水平进行比较的方法。 相对于参考水平的较高水平的NOL3与患者的生存率降低相关,并且相对于参考水平的等同或更低水平的NOL3与患者的增加的存活相关。
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公开(公告)号:US20100179163A1
公开(公告)日:2010-07-15
申请号:US12685411
申请日:2010-01-11
申请人: Andrew KUNG , David ZIEGLER
发明人: Andrew KUNG , David ZIEGLER
IPC分类号: A61K31/496 , C12Q1/68 , C07D401/14 , A61P35/00
CPC分类号: C12Q1/6886 , A61K31/437 , A61K31/496 , A61K31/506 , A61K45/06 , C07D417/02 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N33/5044 , G01N33/57407 , G01N33/57484 , G01N2800/52 , G01N2800/7028 , A61K2300/00
摘要: The present invention features a method for determining the prognosis for survival of a cancer patient. Methods for measuring the level of NOL3 expression in a cancer cell-containing sample from a patient, and comparing the level of NOL3 expression in the sample to a reference level of NOL3 expression are also included. A higher level of NOL3 relative to the reference level correlates with decreased survival of the patient, and an equivalent or lower level of NOL3 relative to the reference level correlates with increased survival of the patient.
摘要翻译: 本发明的特征在于确定癌症患者的存活预后的方法。 还包括用于测量来自患者的含癌细胞的样品中的NOL3表达水平以及将样品中NOL3表达水平与NOL3表达的参考水平进行比较的方法。 相对于参考水平的较高水平的NOL3与患者的生存率降低相关,并且相对于参考水平的等同或更低水平的NOL3与患者的增加的存活相关。
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