利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

2 条记录 (耗时 0.018 秒)

    3,6-disubstituted azabicyclo [3.1.0] hexane deriviatives useful as muscarinic receptor antagonists
    1.
    发明授权
    3,6-disubstituted azabicyclo [3.1.0] hexane deriviatives useful as muscarinic receptor antagonists 失效
    可用作毒蕈碱受体拮抗剂的3,6-二取代的氮杂双环[3.1.0]己烷衍生物

    公开(公告)号：US07410993B2

    公开(公告)日：2008-08-12

    申请号：US10524081

    申请日：2002-08-09

    申请人： Anita Mehta ,  Arundutt V. Silamkoti ,  Miriyala Bruhaspathy ,  Jang Bahadur Gupta

    发明人： Anita Mehta ,  Arundutt V. Silamkoti ,  Miriyala Bruhaspathy ,  Jang Bahadur Gupta

    IPC分类号： A61K31/403 ,  C07D209/52

    CPC分类号： C07D209/02 ,  C07D209/52

    摘要： This invention generally relates to the derivatives of 3,6 disubstituted azabicyclo[3.1.0] hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to a process for the preparation of the compounds of the present invention, pharmaceutical compositions containing the compounds of the present invention and the methods for treating the diseases mediated through muscarinic receptors.

    摘要翻译： 本发明一般涉及3,6-二取代的氮杂双环[3.1.0]己烷的衍生物。 本发明的化合物是毒蕈碱受体拮抗剂，其特别用于治疗通过毒蕈碱受体介导的呼吸，尿和胃肠道系统的各种疾病。 本发明还涉及制备本发明化合物的方法，含有本发明化合物的药物组合物和通过毒蕈碱受体介导的疾病的治疗方法。

    3,6-Disubstituted azabicyclo [3.1.0] hexane derivatives useful as muscarinic receptor
    2.
    发明申请
    3,6-Disubstituted azabicyclo [3.1.0] hexane derivatives useful as muscarinic receptor 失效
    用作毒蕈碱受体的3,6-二取代的氮杂双环[3.1.0]己烷衍生物

    公开(公告)号：US20060142371A1

    公开(公告)日：2006-06-29

    申请号：US10524081

    申请日：2002-08-09

    申请人： Anita Mehta ,  Arundutt Silamkoti ,  Miriyala Bruhaspathy ,  Jang Gupta

    发明人： Anita Mehta ,  Arundutt Silamkoti ,  Miriyala Bruhaspathy ,  Jang Gupta

    IPC分类号： A61K31/403 ,  C07D209/02

    CPC分类号： C07D209/02 ,  C07D209/52

    摘要： This invention generally relates to the derivatives of 3,6 disubstituted azabicyclo[3.1.0]hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to a process for the preparation of the compounds of the present invention, pharmaceutical compositions containing the compounds of the present invention and the methods for treating the diseases mediated through muscarinic receptors.

    摘要翻译： 本发明一般涉及3,6-二取代的氮杂双环[3.1.0]己烷的衍生物。 本发明的化合物是毒蕈碱受体拮抗剂，其特别用于治疗通过毒蕈碱受体介导的呼吸，尿和胃肠道系统的各种疾病。 本发明还涉及制备本发明化合物的方法，含有本发明化合物的药物组合物和通过毒蕈碱受体介导的疾病的治疗方法。