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1.发明授权Preparation and sterilization of green state devices using a supercritical fluid sterilant 有权使用超临界流体灭菌剂制备和灭菌绿色装置公开(公告)号：US07988892B2
公开(公告)日：2011-08-02
申请号：US12277425
申请日：2008-11-25
CPC分类号： A61L2/18
摘要： The invention relates to a method for forming a molded article during sterilization and under high pressure utilizing a supercritical fluid as a sterilization fluid, whereby the pressurization and depressurization rates are controlled to form molded articles.
摘要翻译： 本发明涉及一种在灭菌过程中使用超临界流体作为灭菌流体在灭菌和高压下形成模制品的方法，由此控制加压和减压速率以形成模塑制品。
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2.发明申请Preparation and Sterilization of Green State Devices Using a Supercritical Fluid Sterilant 有权使用超临界流体杀菌剂制备和灭菌绿色状态的设备公开(公告)号：US20090134542A1
公开(公告)日：2009-05-28
申请号：US12277425
申请日：2008-11-25
CPC分类号： A61L2/18
摘要： The invention relates to a method for forming a molded article during sterilization and under high pressure utilizing a supercritical fluid as a sterilization fluid, whereby the pressurization and depressurization rates are controlled to form molded articles.
摘要翻译： 本发明涉及一种在灭菌过程中使用超临界流体作为灭菌流体在灭菌和高压下形成模制品的方法，由此控制加压和减压速率以形成模塑制品。
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3.发明授权公开(公告)号：US07771652B2
公开(公告)日：2010-08-10
申请号：US12101489
申请日：2008-04-11
IPC分类号： A61L2/20
CPC分类号： A61L2/18 , A61L2/208 , A61L2430/02
摘要： A method is disclosed that produces allografts from matrices typically containing demineralized bone matrix (DBM) powder, demineralized bone matrix gel, demineralized bone matrix paste, bone cement, cancellous bone, or cortical bone and mixtures thereof. The matrices are sterilized utilizing supercritical CO2 in the presence of a sterilizing additive and an entrainer such as an alkaline earth metal compound, preferably CaCO3. The resultant allograft materials have a reduced rate of rejection when used in allograft procedures including, bone, cartilage, tendon, and ligament grafting procedures.
摘要翻译： 公开了一种从通常含有软化骨基质（DBM）粉末，软化骨基质凝胶，软化骨基质糊剂，骨水泥，松质骨或皮质骨及其混合物的基质产生同种异体移植物的方法。 在灭菌添加剂和夹带剂如碱土金属化合物，优选CaCO 3存在下，使用超临界CO 2对基质进行灭菌。 当用于同种异体移植手术（包括骨，软骨，腱和韧带移植手术）时，所得到的同种异体移植材料的排斥率降低。
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4.发明申请公开(公告)号：US20090257914A1
公开(公告)日：2009-10-15
申请号：US12101489
申请日：2008-04-11
IPC分类号： A61L2/20
CPC分类号： A61L2/18 , A61L2/208 , A61L2430/02
摘要： A method is disclosed that produces allografts from matrices typically containing demineralized bone matrix (DBM) powder, demineralized bone matrix gel, demineralized bone matrix paste, bone cement, cancellous bone, or cortical bone and mixtures thereof. The matrices are sterilized utilizing supercritical CO2 in the presence of a sterilizing additive and an entrainer such as an alkaline earth metal compound, preferably CaCO3. The resultant allograft materials have a reduced rate of rejection when used in allograft procedures including, bone, cartilage, tendon, and ligament grafting procedures.
摘要翻译： 公开了一种从通常含有软化骨基质（DBM）粉末，软化骨基质凝胶，软化骨基质糊剂，骨水泥，松质骨或皮质骨及其混合物的基质产生同种异体移植物的方法。 在灭菌添加剂和夹带剂如碱土金属化合物，优选CaCO 3存在下，使用超临界CO 2对基质进行灭菌。 当用于同种异体移植手术（包括骨，软骨，腱和韧带移植手术）时，所得到的同种异体移植材料的排斥率降低。
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