公开(公告)号：US08609437B2

公开(公告)日：2013-12-17

申请号：US12812394

申请日：2009-01-21

Applicant: Anthony T. Yeung ,  Jeffrey Tokar

Inventor： Anthony T. Yeung ,  Jeffrey Tokar

IPC: G01N33/68 ,  G01N33/00 ,  G01N33/543 ,  C40B40/10 ,  C40B40/00

CPC classification number: G01N33/487 ,  C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/158 ,  G01N33/00 ,  G01N33/48

Abstract: Compositions and methods for use in methods and kits for the detection of an increased risk of pancreatic cancer are provided. Cyst fluid samples isolated from patients that are positive for at least three of the following markers, mucin 1, mucin 2, mucin 5AC, mucin 5B, mucin 6, CEA CAM 1, CEACAM 5, CEACAM 6, CEACAM 7, CEACAM 8, S100-A6, S100-A8, S100-A9 and S100-A11 indicate that such patients are at greater risk for the development of pancreatic cancer when compared to cyst fluid samples isolated from patients lacking these markers.

Abstract translation: 提供了用于检测胰腺癌风险增加的方法和试剂盒中的组合物和方法。 对于至少三种以下标记为阳性的患者分离的囊液液样品，粘蛋白1，粘蛋白2，粘蛋白5AC，粘蛋白5B，粘蛋白6，CEA CAM 1，CEACAM 5，CEACAM 6，CEACAM 7，CEACAM 8，S100 -A6，S100-A8，S100-A9和S100-A11表明，与从缺乏这些标记物的患者分离的囊肿液样品相比，这些患者胰腺癌的发展风险更高。

公开(公告)号：US20110008914A1

公开(公告)日：2011-01-13

申请号：US12812394

申请日：2009-01-21

Applicant: Anthony T. Yeung ,  Jeffrey Tokar

Inventor： Anthony T. Yeung ,  Jeffrey Tokar

IPC: G01N33/68 ,  G01N33/543 ,  C07H21/04 ,  C40B40/10

CPC classification number: G01N33/487 ,  C12Q1/68 ,  C12Q1/6886 ,  C12Q2600/158 ,  G01N33/00 ,  G01N33/48

Abstract: Compositions and methods which indicate an increased risk for pancreatic carcinoma are disclosed.

Abstract translation: 公开了表明胰腺癌风险增加的组合物和方法。