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    INTRAVAGINAL DEVICES COMPRISING ANTICHOLINERGIC AGENTS, AND METHODS OF MAKING THEREOF
    3.
    发明申请
    INTRAVAGINAL DEVICES COMPRISING ANTICHOLINERGIC AGENTS, AND METHODS OF MAKING THEREOF 审中-公开
    包含抗胆碱剂的内装置及其制备方法

    公开(公告)号：US20120053534A1

    公开(公告)日：2012-03-01

    申请号：US13166309

    申请日：2011-06-22

    申请人： Anu Mahashabde ,  Jiaxiang Tsao

    发明人： Anu Mahashabde ,  Jiaxiang Tsao

    IPC分类号： A61M31/00 ,  B28B1/14

    CPC分类号： A61K9/0036

    摘要： The present invention is directed to an intravaginal device comprising: (a) an annular first matrix comprising a pocket and a pocket wall, wherein the pocket wall has a uniform thickness, and wherein the pocket wall encompasses the pocket; and (b) a second matrix comprising an anticholinergic agent, wherein the second matrix is located in the pocket.The present invention is also directed to a method of making an intravaginal device, the method comprising: (a) placing a first matrix into a mold, the mold being shaped so as to form an annular intravaginal device comprising a pocket and a pocket wall, wherein the pocket wall has a uniform thickness, and wherein the pocket wall encompasses the pocket; (b) curing the first matrix; (c) placing a second matrix comprising an anticholinergic agent in the pocket; and (d) curing the second matrix.

    摘要翻译： 本发明涉及一种阴道内装置，其包括：（a）环形第一矩阵，其包括口袋和口袋壁，其中所述口袋壁具有均匀的厚度，并且其中所述口袋壁包围所述口袋; 和（b）包含抗胆碱剂的第二基质，其中所述第二基质位于所述口袋中。 本发明还涉及一种制造阴道内装置的方法，所述方法包括：（a）将第一基质放置在模具中，所述模具成形为形成包括口袋和口袋壁的环形阴道内装置， 其中所述口袋壁具有均匀的厚度，并且其中所述口袋壁包围所述口袋; （b）固化第一基质; （c）将包含抗胆碱剂的第二基质置于口袋中; 和（d）固化第二基质。

    Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
    5.
    发明申请
    Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof 审中-公开
    阴道内装置的坚固支持，制作方法和用途

    公开(公告)号：US20100040671A1

    公开(公告)日：2010-02-18

    申请号：US12539568

    申请日：2009-08-11

    申请人： Salah U. AHMED ,  Jiaxiang Tsao

    发明人： Salah U. AHMED ,  Jiaxiang Tsao

    IPC分类号： A61F6/14 ,  B28B1/14 ,  A61F6/06

    CPC分类号： A61K9/0036 ,  A61K31/565 ,  A61K31/57

    摘要： The present invention relates to intravaginal devices having a rigid support, methods of making, and uses thereof. The devices comprise (a) a rigid support having a Shore A Hardness of at least about 20 and a tensile strength of at least about 1 MPa, (b) a matrix, and (c) an active agent dispersed in the matrix, wherein the support and the matrix are adjacent and wherein the device is annular.

    摘要翻译： 本发明涉及具有刚性支撑物的阴道内装置，制造方法及其应用。 这些装置包括（a）肖氏A硬度至少为约20，拉伸强度为至少约1MPa的刚性载体，（b）基体，和（c）分散在基质中的活性剂，其中 支撑体和基体相邻并且其中该装置是环形的。

    BARREL-SHAPED VAGINAL RING
    6.
    发明申请
    BARREL-SHAPED VAGINAL RING 有权
    巴格尔形状的VAGINAL RING

    公开(公告)号：US20130269706A1

    公开(公告)日：2013-10-17

    申请号：US13818044

    申请日：2011-08-18

    申请人： Jiaxiang Tsao

    发明人： Jiaxiang Tsao

    IPC分类号： A61F6/14

    CPC分类号： A61F6/142 ,  A61K9/0036 ,  A61K31/167 ,  A61K31/216 ,  A61K31/565 ,  A61K31/569 ,  A61K31/58

    摘要： The present invention relates to annular intravaginal devices comprising an aperture, methods of making, and uses thereof. The annular devices comprise an aperture extending into the device, the aperture having: (a) an interior diameter, and (b) an exterior entry diameter, wherein the exterior entry diameter of the aperture is less than the interior diameter of the aperture.

    摘要翻译： 本发明涉及包括孔的环形阴道内装置，其制造方法和用途。 环形装置包括延伸到装置中的孔，孔具有：（a）内径，和（b）外入口直径，其中孔的外部入口直径小于孔的内径。