公开(公告)号：US11542233B2

公开(公告)日：2023-01-03

申请号：US16472501

申请日：2017-12-22

申请人： Aquinnah Pharmaceuticals, Inc.

发明人： Duane A. Burnett ,  Joseph P. Vacca

IPC分类号： C07D209/42 ,  C07D235/24 ,  C07D405/12 ,  C07D413/12 ,  C07D471/04

摘要： Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

公开(公告)号：US20170360726A1

公开(公告)日：2017-12-21

申请号：US15533354

申请日：2015-12-04

申请人： Aquinnah Pharmaceuticals, Inc.

发明人： Glenn R. Larsen ,  Manfred Weigele ,  Joseph P. Vacca

IPC分类号： A61K31/18 ,  A61K31/4025 ,  A61K31/44 ,  C07D213/71

CPC分类号： A61K31/18 ,  A61K31/4025 ,  A61K31/44 ,  C07D213/71 ,  C07D295/108

摘要： Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

公开(公告)号：US20230303489A1

公开(公告)日：2023-09-28

申请号：US17982187

申请日：2022-11-07

申请人： Aquinnah Pharmaceuticals, Inc.

发明人： Duane A. Burnett ,  Joseph P. Vacca

IPC分类号： C07D209/42 ,  C07D235/24 ,  C07D405/12 ,  C07D413/12 ,  C07D471/04

CPC分类号： C07D209/42 ,  C07D235/24 ,  C07D405/12 ,  C07D413/12 ,  C07D471/04

摘要： Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

公开(公告)号：US20200270211A1

公开(公告)日：2020-08-27

申请号：US16472501

申请日：2017-12-22

申请人： Aquinnah Pharmaceuticals, Inc.

发明人： Duane A. Burnett ,  Joseph P. Vacca

IPC分类号： C07D209/42 ,  C07D471/04 ,  C07D235/24 ,  C07D405/12 ,  C07D413/12

摘要： Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

公开(公告)号：US20180305334A1

公开(公告)日：2018-10-25

申请号：US15767905

申请日：2016-10-14

申请人： Aquinnah Pharmaceuticals, Inc.

发明人： Glenn R. Larsen ,  Manfred Weigele ,  Joseph P. Vacca ,  Duane A. Burnett ,  Amy Ripka

IPC分类号： C07D401/12 ,  C07D417/04 ,  C07D295/145 ,  C07D209/42 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D407/12 ,  C07D407/14 ,  C07D409/12 ,  C07D413/12 ,  C07D471/04 ,  A61P43/00

CPC分类号： C07D401/12 ,  A61P43/00 ,  C07D209/42 ,  C07D295/145 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D407/12 ,  C07D407/14 ,  C07D409/12 ,  C07D413/12 ,  C07D417/04 ,  C07D471/04

摘要： Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

公开(公告)号：US20170369474A1

公开(公告)日：2017-12-28

申请号：US15533339

申请日：2015-12-04

申请人： Aquinnah Pharmaceuticals, Inc.

发明人： Glenn R. Larsen ,  Manfred Weigele ,  Joseph P. Vacca

IPC分类号： C07D403/06 ,  C07D207/36

CPC分类号： C07D403/06 ,  C07D207/34 ,  C07D207/36

摘要： Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.