公开(公告)号：US20240301007A1

公开(公告)日：2024-09-12

申请号：US18427625

申请日：2024-01-30

Applicant: Arcturus Therapeutics, Inc.

Inventor： Brian SULLIVAN ,  Sean SULLIVAN ,  Daiki MATSUDA ,  Rodrigo YELIN ,  Jinho PARK

IPC: C07K14/005 ,  A61K9/127 ,  A61P31/16

CPC classification number: C07K14/005 ,  A61K9/1272 ,  A61P31/16 ,  C12N2760/16121 ,  C12N2760/16134 ,  C12N2770/36122 ,  C12N2770/36134

Abstract: Provided herein are RNA molecules encoding viral replication proteins and antigenic proteins or fragments thereof. Also provided herein are compositions that include RNA molecules encoding viral replication proteins and antigenic proteins or fragments thereof, and lipids. RNA molecules and compositions including them are useful for inducing immune responses.