公开(公告)号：US11547997B2

公开(公告)日：2023-01-10

申请号：US16603338

申请日：2018-04-06

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Alexander A. Green ,  Matthew Gilliam ,  Kirstie Swingle ,  Nicholas Stephanopoulos ,  Neal Woodbury

IPC: B01L3/00 ,  C12Q1/70 ,  G01N33/543

Abstract: Integrated diagnostic devices comprising peptide-DNA conjugates for analyte detection, an embedded biomolecular computing system for sample analysis, and a layered device architecture are provided herein. In particular, provided herein are devices comprising a layered architecture that enables diagnostic reagents, sample components, and reaction products to flow through the system with minimal user intervention.