公开(公告)号：US20240317767A1

公开(公告)日：2024-09-26

申请号：US18670264

申请日：2024-05-21

申请人： AstraZeneca AB

发明人： Johan Olof BRODDEFALK ,  Hans Fredrik EMTENÂS ,  Kenneth Lars GRANBERG ,  Malin Anita LEMURELL ,  Daniel Tor PETTERSEN ,  Alleyn Thomas PLOWRIGHT ,  Lars Johan Andreas ULANDER

IPC分类号： C07D487/04 ,  A61K31/4155 ,  A61K31/4985 ,  A61P9/00 ,  A61P9/10 ,  A61P11/00 ,  C07D231/40 ,  C07D231/44 ,  C07D231/50 ,  C07D413/12 ,  C07D417/12 ,  C07D498/04

CPC分类号： C07D487/04 ,  A61K31/4155 ,  A61K31/4985 ,  A61P9/00 ,  A61P9/10 ,  A61P11/00 ,  C07D231/40 ,  C07D231/44 ,  C07D231/50 ,  C07D413/12 ,  C07D417/12 ,  C07D498/04

摘要： The present application relates to novel compounds of formula (I)




to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.

公开(公告)号：US20230219967A1

公开(公告)日：2023-07-13

申请号：US18174832

申请日：2023-02-27

申请人： AstraZeneca AB

发明人： Johan Olof BRODDEFALK ,  Hans Fredrik EMTENÂS ,  Kenneth Lars GRANBERG ,  Malin Anita LEMURELL ,  Daniel Tor PETTERSEN ,  Alleyn Thomas PLOWRIGHT ,  Lars Johan Andreas ULANDER

IPC分类号： C07D487/04 ,  C07D413/12 ,  C07D498/04 ,  A61P11/00 ,  C07D231/40 ,  C07D231/44 ,  C07D417/12 ,  A61P9/00 ,  C07D231/50 ,  A61K31/4155 ,  A61P9/10 ,  A61K31/4985

CPC分类号： C07D487/04 ,  C07D413/12 ,  C07D498/04 ,  A61P11/00 ,  C07D231/40 ,  C07D231/44 ,  C07D417/12 ,  A61P9/00 ,  C07D231/50 ,  A61K31/4155 ,  A61P9/10 ,  A61K31/4985

摘要： The present application relates to novel compounds of formula (I)




to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.

公开(公告)号：US20200157113A1

公开(公告)日：2020-05-21

申请号：US16668743

申请日：2019-10-30

申请人： ASTRAZENECA AB

发明人： Johan Olof BRODDEFALK ,  Hans Fredrik EMTENÂS ,  Kenneth Lars GRANBERG ,  Malin Anita LEMURELL ,  Daniel Tor PETTERSEN ,  Alleyn Thomas PLOWRIGHT ,  Lars Johan Andreas ULANDER

IPC分类号： C07D487/04 ,  C07D498/04 ,  C07D417/12 ,  C07D413/12 ,  C07D231/50 ,  C07D231/44 ,  C07D231/40

摘要： The present application relates to novel compounds of formula (I) to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.

公开(公告)号：US20190084991A1

公开(公告)日：2019-03-21

申请号：US16196217

申请日：2018-11-20

申请人： ASTRAZENECA AB

发明人： Johan Olof BRODDEFALK ,  Hans Fredrik EMTENÂS ,  Kenneth Lars GRANBERG ,  Malin Anita LEMURELL ,  Daniel Tor PETTERSEN ,  Alleyn Thomas PLOWRIGHT ,  Lars Johan Andreas ULANDER

IPC分类号： C07D487/04 ,  C07D231/44 ,  C07D231/40 ,  C07D498/04 ,  C07D231/50 ,  C07D417/12 ,  C07D413/12

摘要： The present application relates to novel compounds of formula (I) to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.

公开(公告)号：US20180237439A1

公开(公告)日：2018-08-23

申请号：US15571291

申请日：2016-05-03

申请人： ASTRAZENECA AB

发明人： Johan Olof BRODDEFALK ,  Hans Fredrik EMTENÄS ,  Kenneth Lars GRANBERG ,  Malin Anita LEMURELL ,  Daniel Tor PETTERSEN ,  Alleyn Thomas PLOWRIGHT ,  Lars Johan Andreas ULANDER

IPC分类号： C07D487/04 ,  C07D498/04 ,  C07D413/12 ,  C07D417/12

CPC分类号： C07D487/04 ,  C07D231/40 ,  C07D231/44 ,  C07D231/50 ,  C07D413/12 ,  C07D417/12 ,  C07D498/04

摘要： The present application relates to novel compounds of formula (I) to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.