Excipients for nicotine-containing therapeutic compositions

    公开(公告)号:US09907748B2

    公开(公告)日:2018-03-06

    申请号:US13278877

    申请日:2011-10-21

    IPC分类号: A61K31/465 A61K9/00 A61K9/68

    摘要: A composition intended to be employed for therapeutic purposes incorporates an active ingredient (e.g., a source of nicotine) and at a non-active ingredient that is carried by a porous substrate. The non-active ingredient can be a substance that has the capability of affecting the pH of the biological system to which it is applied (e.g., basic substance and/or buffering agent is sorbed onto the porous carrier, so as to be in intimate contact with that carrier). Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) and nicotine polacrilex. The basic substance can be sodium carbonate, and the porous substrate can be microcrystalline cellulose. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and can be used as a nicotine replacement therapy.

    Translucent smokeless tobacco product
    2.
    发明授权
    Translucent smokeless tobacco product 有权
    半透明无烟烟草制品

    公开(公告)号:US09084439B2

    公开(公告)日:2015-07-21

    申请号:US13240525

    申请日:2011-09-22

    IPC分类号: A24B15/00 A24B15/24 A24B15/30

    CPC分类号: A24B15/24 A24B15/10 A24B15/30

    摘要: The invention provides a smokeless tobacco product comprising a tobacco extract. In some embodiments, the smokeless tobacco product is translucent. The invention further provides methods for making and using the smokeless tobacco product. In certain embodiments, the smokeless tobacco product comprises isomalt, maltitol syrup, and a translucent tobacco extract prepared by ultrafiltration.

    摘要翻译: 本发明提供了一种包含烟草提取物的无烟烟草制品。 在一些实施方案中,无烟烟草制品是半透明的。 本发明还提供了制造和使用无烟烟草制品的方法。 在某些实施方案中,无烟烟草制品包含异麦芽糖酮,麦芽糖醇糖浆和通过超滤制备的半透明烟草提取物。

    Translucent smokeless tobacco product
    3.
    发明授权
    Translucent smokeless tobacco product 有权
    半透明无烟烟草制品

    公开(公告)号:US09474303B2

    公开(公告)日:2016-10-25

    申请号:US13614673

    申请日:2012-09-13

    摘要: A smokeless tobacco product is provided that includes a tobacco material in the form of a tobacco extract, a particulate tobacco material, or a combination thereof. In some embodiments, the smokeless tobacco product is substantially translucent. Methods for making and using the smokeless tobacco product are also provided. The smokeless tobacco product can include isomalt, maltitol syrup, particulate tobacco, and a translucent tobacco extract prepared by ultrafiltration.

    摘要翻译: 提供了一种无烟烟草产品,其包括烟草提取物形式的烟草材料,烟草颗粒物质或其组合。 在一些实施方案中,无烟烟草制品基本上是半透明的。 还提供了制造和使用无烟烟草制品的方法。 无烟烟草产品可以包括异麦芽糖醇,麦芽糖醇糖浆,颗粒烟草,以及通过超滤制备的半透明烟草提取物。