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公开(公告)号：US11642244B2
公开(公告)日：2023-05-09
申请号：US16987370
申请日：2020-08-06
Applicant: Avedro, Inc.
Inventor： Desmond C. Adler , Mikhail Smirnov , David Usher , Behrouz Tavakol , Jason Hill , Jie Zhang , Amit Mukherjee , Alex Yildizyan
IPC: A61F9/008
CPC classification number: A61F9/008 , A61F2009/00844 , A61F2009/00872 , A61F2009/00897
Abstract: A system for treating an eye includes a laser light source providing photoactivating light. The system includes a scanning system to receive the photoactivating light as a laser beam and to move the laser beam over a cornea treated with a cross-linking agent. The system includes a controller that provides control signal(s) to programmatically control the laser light source and the scanning system. The control signal(s) cause the laser beam to visit region(s) of the cornea more than once according to a scan pattern and expose the region(s) to the photoactivating light. The photoactivating light causes the cross-linking agent in the exposed region(s) to react with oxygen to generate cross-linking activity in the exposed region(s). The scan pattern causes a predetermined period of time to pass between visits by the laser beam to the exposed region(s), the predetermined period of time allowing oxygen in the exposed region(s) to replenish.
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公开(公告)号：US20210038428A1
公开(公告)日：2021-02-11
申请号：US16987370
申请日：2020-08-06
Applicant: Avedro, Inc.
Inventor： Desmond C. Adler , Mikhail Smirnov , David Usher , Behrouz Tavakol , Jason Hill , Jie Zhang , Amit Mukherjee , Alex Yildizyan
IPC: A61F9/008
Abstract: A system for treating an eye includes a laser light source providing photoactivating light. The system includes a scanning system to receive the photoactivating light as a laser beam and to move the laser beam over a cornea treated with a cross-linking agent. The system includes a controller that provides control signal(s) to programmatically control the laser light source and the scanning system. The control signal(s) cause the laser beam to visit region(s) of the cornea more than once according to a scan pattern and expose the region(s) to the photoactivating light. The photoactivating light causes the cross-linking agent in the exposed region(s) to react with oxygen to generate cross-linking activity in the exposed region(s). The scan pattern causes a predetermined period of time to pass between visits by the laser beam to the exposed region(s), the predetermined period of time allowing oxygen in the exposed region(s) to replenish.
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Patent Agency Ranking
公开(公告)号：US20210369108A1
公开(公告)日：2021-12-02
申请号：US17278152
申请日：2019-09-19
Applicant: Avedro, Inc.
Inventor： Amit Mukherjee , Vladimir Ruzhitsky , David Usher
Abstract: An example system for tracking motion of an eye during an eye treatment includes an image capture device configured to capture a plurality of images of an eye. The system includes controller(s) including processor(s) that receive the plurality of images from the image capture device. The processor(s) implement a plurality of trackers. Each tracker is configured to detect a respective feature in the plurality of images and provide, based on the respective feature, a respective set of data relating to motion of the eye. The respective features detected by the plurality of trackers are orthogonal relative to each other and the respective sets of data provided by the plurality of trackers are independent of each other. The processor(s) coalesce the sets of data from the plurality of trackers and determine an indicator of the motion of the eye based on the coalesced sets of data.
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公开(公告)号：US12144546B2
公开(公告)日：2024-11-19
申请号：US17278152
申请日：2019-09-19
Applicant: Avedro, Inc.
Inventor： Amit Mukherjee , Vladimir Ruzhitsky , David Usher
Abstract: An example system for tracking motion of an eye during an eye treatment includes an image capture device configured to capture a plurality of images of an eye. The system includes controller(s) including processor(s) that receive the plurality of images from the image capture device. The processor(s) implement a plurality of trackers. Each tracker is configured to detect a respective feature in the plurality of images and provide, based on the respective feature, a respective set of data relating to motion of the eye. The respective features detected by the plurality of trackers are orthogonal relative to each other and the respective sets of data provided by the plurality of trackers are independent of each other. The processor(s) coalesce the sets of data from the plurality of trackers and determine an indicator of the motion of the eye based on the coalesced sets of data.
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公开(公告)号：US20230346601A1
公开(公告)日：2023-11-02
申请号：US18313078
申请日：2023-05-05
Applicant: Avedro, Inc.
Inventor： Desmond C. Adler , Mikhail Smirnov , David Usher , Behrouz Tavakol , Jason Hill , Jie Zhang , Amit Mukherjee , Alex Yildizyan
IPC: A61F9/008
CPC classification number: A61F9/008 , A61F2009/00844 , A61F2009/00897 , A61F2009/00872
Abstract: A system for treating an eye includes a laser light source providing photoactivating light. The system includes a scanning system to receive the photoactivating light as a laser beam and to move the laser beam over a cornea treated with a cross-linking agent. The system includes a controller that provides control signal(s) to programmatically control the laser light source and the scanning system. The control signal(s) cause the laser beam to visit region(s) of the cornea more than once according to a scan pattern and expose the region(s) to the photoactivating light. The photoactivating light causes the cross-linking agent in the exposed region(s) to react with oxygen to generate cross-linking activity in the exposed region(s). The scan pattern causes a predetermined period of time to pass between visits by the laser beam to the exposed region(s), the predetermined period of time allowing oxygen in the exposed region(s) to replenish.
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公开(公告)号：US20250161114A1
公开(公告)日：2025-05-22
申请号：US19030052
申请日：2025-01-17
Applicant: Avedro, Inc.
Inventor： Desmond C. Adler , Mikhail Smirnov , David Usher , Behrouz Tavakol , Jason Hill , Jie Zhang , Amit Mukherjee , Alex Yildizyan
IPC: A61F9/008
Abstract: A system for treating an eye includes a laser light source providing photoactivating light. The system includes a scanning system to receive the photoactivating light as a laser beam and to move the laser beam over a cornea treated with a cross-linking agent. The system includes a controller that provides control signal(s) to programmatically control the laser light source and the scanning system. The control signal(s) cause the laser beam to visit region(s) of the cornea more than once according to a scan pattern and expose the region(s) to the photoactivating light. The photoactivating light causes the cross-linking agent in the exposed region(s) to react with oxygen to generate cross-linking activity in the exposed region(s). The scan pattern causes a predetermined period of time to pass between visits by the laser beam to the exposed region(s), the predetermined period of time allowing oxygen in the exposed region(s) to replenish.
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公开(公告)号：US20250072751A1
公开(公告)日：2025-03-06
申请号：US18951035
申请日：2024-11-18
Applicant: Avedro, Inc.
Inventor： Amit Mukherjee , Vladimir Ruzhitsky , David Usher
Abstract: An example system for tracking motion of an eye during an eye treatment includes an image capture device configured to capture a plurality of images of an eye. The system includes an ensemble tracker employing a first, second, and third tracker to process a plurality of images. Each tracker is configured to detect a respective feature in the plurality of images and provide, based on the respective feature, a respective set of data relating to motion of the eye. The first tracker detects a first feature including an anatomical structure in an iris region of the eye. The second tracker detects a second feature including a shape defined by a contrast between the iris region and a pupil region. A third tracker detects a third feature including a boundary between the iris region and the pupil region of the eye.
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