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公开(公告)号:US20220395580A1
公开(公告)日:2022-12-15
申请号:US17364765
申请日:2021-06-30
发明人: Andrew John GEALL , Venkata Ramana DOPPALAPUDI , Joel Daniel ARIAS , David Sai-Ho CHU , Michael Caramian COCHRAN , Rob BURKE , Philip KOVACH , Barbora MALECOVA
IPC分类号: A61K47/68 , C07K16/28 , C12N15/113 , C07H17/00 , A61K47/64 , A61K31/713 , A61P35/00 , A61K47/60
摘要: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.