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公开(公告)号:US20230093302A1
公开(公告)日:2023-03-23
申请号:US17904972
申请日:2021-02-25
IPC分类号: C07D403/12 , A61K45/06
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MAO-B.
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2.
公开(公告)号:US20230074698A1
公开(公告)日:2023-03-09
申请号:US17929005
申请日:2021-02-10
发明人: Muge Didem ORHAN , Timucin AVSAR , Berna DOGAN , Gurbet CACAN , Seyma CALIS , Serdar DURDAGI
IPC分类号: C07D209/20 , A61K31/404 , A61K45/06 , A61P35/00
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of BCL-2.
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公开(公告)号:US20230063449A1
公开(公告)日:2023-03-02
申请号:US17904404
申请日:2021-02-17
发明人: Serdar DURDAGI , Timucin AVSAR , Mine YURTSEVER , Gulsah AYDIN , Maide Nur PAKSOY , Muge Didem ORHAN
IPC分类号: A61K31/405 , C07D209/20 , A61K45/06 , A61P35/00
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
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公开(公告)号:US20240270730A1
公开(公告)日:2024-08-15
申请号:US17904419
申请日:2021-02-17
发明人: Serdar DURDAGI , Muge Didem ORHAN , Timucin AVSAR , Mine YURTSEVER , Maide Nur PAKSOY , Gulsah AYDIN
IPC分类号: C07D413/12 , A61K31/4245 , A61K45/06 , A61P35/00
CPC分类号: C07D413/12 , A61K31/4245 , A61K45/06 , A61P35/00
摘要: The invention relates to compound shown with formula I or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
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5.
公开(公告)号:US20230099876A1
公开(公告)日:2023-03-30
申请号:US17929003
申请日:2021-02-10
发明人: Muge Didem ORHAN , Serdar DURDAGI , Berna DOGAN , Seyma CALIS , Gurbet CACAN , Timucin AVSAR
IPC分类号: C07D409/14 , A61K31/4709 , A61K45/06 , A61P35/00
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of BCL-2.
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公开(公告)号:US20230073261A1
公开(公告)日:2023-03-09
申请号:US17904403
申请日:2021-02-16
发明人: Timucin AVSAR , Serdar DURDAGI , Muge Didem ORHAN , Maide Nur PAKSOY , Gulsah AYDIN , Mine YURTSEVER
IPC分类号: C07D209/18 , A61P35/02 , A61K45/06
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
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公开(公告)号:US20230071340A1
公开(公告)日:2023-03-09
申请号:US17800378
申请日:2021-02-17
发明人: Serdar DURDAGI , Timucin AVSAR , Muge Didem ORHAN , Maide Nur PAKSOY , Gulsah AYDIN , Mine YURTSEVER
IPC分类号: A61K31/501 , C07D403/12 , A61P35/00 , A61K45/06
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
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公开(公告)号:US20230098888A1
公开(公告)日:2023-03-30
申请号:US17800373
申请日:2021-02-17
发明人: Mine YURTSEVER , Muge Didem ORHAN , Maide Nur PAKSOY , Gulsah AYDIN , Timucin AVSAR , Serdar DURDAGI
IPC分类号: A61K31/517 , C07D403/12 , A61P35/00 , A61K45/06
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
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公开(公告)号:US20230067644A1
公开(公告)日:2023-03-02
申请号:US17904423
申请日:2021-02-17
发明人: Serdar DURDAGI , Muge ORHAN , Timucin AVSAR , Maide PAKSOY , Gulsah AYDIN , Mine YURTSEVER
IPC分类号: C07D209/04 , A61K45/06
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.
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10.
公开(公告)号:US20230090414A1
公开(公告)日:2023-03-23
申请号:US17760464
申请日:2021-02-10
发明人: Berna DOGAN , Serdar DURDAGI , Gurbet CACAN , Seyma CALIS , Timucin AVSAR , Muge Didem ORHAN
IPC分类号: A61K31/426 , C07D277/54 , A61K45/06 , A61P35/00
摘要: The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of BCL-2.
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