公开(公告)号：US3668246A

公开(公告)日：1972-06-06

申请号：US3668246D

申请日：1968-08-12

Applicant: BASF AG

Inventor： BERDING CHRISTOPH ,  GUENTHERT PAUL ,  KOEHLER WALDEMAR ,  SCHULZ GERHARD

IPC: C07C101/20

Abstract: Continuous production of alkali metal salts of nitrilotriacetic acid from an alkali metal cyanide, formaldehyde and ammonia by reaction of the components in at least two stages, the alkali metal cyanide being reacted with formaldehyde in stoichiometric or substantially stoichiometric ratio at temperatures of 50* to 200* and pressures of from atmospheric pressure to 50 atmospheres gauge in the presence of an excess of ammonia in the first stage and (while simultaneously removing ammonia) further amounts of alkali metal cyanide and formaldehyde being allowed to act at temperatures of 60* to 110*C in one or more subsequent stages, 5 to 35 mole percent of the total amount of alkali metal cyanide required being replaced by free hydrocyanic acid and/or hydroxyacetonitrile.

Abstract translation: 在至少两个阶段通过组分的反应从碱金属氰化物，甲醛和氨连续生产次氮基三乙酸的碱金属盐，碱金属氰化物与化学计量或基本上化学计量比的甲醛与50至200℃的温度反应 DEG和在大气压至50大气压的压力下，在第一阶段存在过量的氨的情况下，（同时除去氨），另外量的碱金属氰化物和甲醛允许在60〜110℃的温度下作用 在一个或多个后续阶段中，所需的碱金属氰化物的总量的5-35摩尔％被游离氢氰酸和/或羟基乙腈代替。

公开(公告)号：US3689543A

公开(公告)日：1972-09-05

申请号：US3689543D

申请日：1969-08-08

Applicant: BASF AG

Inventor： BERDING CHRISTOPH ,  GUENTHERT PAUL ,  SCHULZ GERHARD ,  KOEHLER WALDEMAR

IPC: C07C101/20

CPC classification number: C11D3/33

Abstract: Production of alkali metal salts of nitrilotriacetic acid from an alkali metal cyanide, formaldehyde and ammonia by reaction in at least two stages, the alkali metal cyanide being reacted with formaldehyde in approximately stoichiometric ratio of 50* to 200* C. and 2 to 50 atmospheres gauge in the presence of an excess of ammonia in the first stage and the resultant solution (after decompression to atmospheric pressure) being treated in one or more further stages with further amounts of alkali metal cyanide and formaldehyde at 60* to 110* C. while removing ammonia at the same time.

Abstract translation: 通过至少两个阶段的反应，从碱金属氰化物，甲醛和氨生产次氮基三乙酸的碱金属盐，使碱金属氰化物与甲醛反应，化学计量比约为50至200℃和2至50个大气压 在第一阶段存在过量的氨，并在所得溶液（在减压至大气压之后）在一个或多个其它阶段用更多量的碱金属氰化物和甲醛在60℃至110℃下进行处理，同时 同时去除氨。

公开(公告)号：US3607930A

公开(公告)日：1971-09-21

申请号：US3607930D

申请日：1968-07-08

Applicant: BASF AG

Inventor： BERDING CHRISTOPH ,  GUENTHERT PAUL ,  KOEHLER WALDEMAR ,  SCHULZ GERHARD

IPC: C07C101/20

CPC classification number: C11D3/33

Abstract: A continuous process for the production of alkali metal salts of nitrilotriacetic acid by reaction in a first stage of alkali metal cyanide, formaldehyde and excess ammonia at superatmospheric pressure and elevated temperature to form an aminoacetic acid solution, followed by depressurizing and treating the solution obtained with further amounts of alkali metal cyanide and formaldehyde while removing the ammonia formed until conversion to nitrilotriacetic acid is complete.