公开(公告)号：US20160107986A1

公开(公告)日：2016-04-21

申请号：US14892114

申请日：2014-05-20

Applicant: BAYER CROPSCIENCE Aktiengesellschaft

Inventor： Albert SCHNATTERER ,  Dieter HEINZ ,  Martin LITTMANN ,  Ulrich PHILIPP ,  Juergen LUDWIG ,  Constantin FRERICK ,  Michael BARZ

IPC: C07C249/08 ,  C07F9/09

CPC classification number: C07C249/08 ,  C07F9/09 ,  C07C251/48 ,  C07C251/36 ,  C07C251/44

Abstract: Method for preparing certain oximes and oxime O-methyl ethers by reacting poorly water-soluble carbonyl compounds with salts of hydroxylamine or hydroxylamine O-methyl ether or the free base of hydroxylamine in the presence of certain phosphoric esters or salts thereof of the formula (I) wherein R1, R2 and X are defined as specified in the description.

Abstract translation: 通过使难溶于水的羰基化合物与羟胺或羟胺的盐O-甲基醚或羟胺的游离碱在式（I）的某些磷酸酯或其盐存在下反应来制备某些肟和肟O-甲基醚的方法 ）其中R1，R2和X如说明书中所述定义。

公开(公告)号：US20210163430A1

公开(公告)日：2021-06-03

申请号：US17045069

申请日：2019-04-02

Applicant: Bayer Aktiengesellschaft ,  Bayer CropScience Aktiengesellschaft

Inventor： Taraneh FARIDA ,  Martin LITTMANN ,  Ali SANLI ,  Kyra Larissa PABST ,  Juergen LUDWIG ,  Albert SCHNATTERER

IPC: C07D275/03

Abstract: The present invention relates to a novel, one-stage method for preparing and isolating 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide (isotianil), which has microbicidal and plant-fortifying (host defence inducer) properties. In the method according to the invention, the amount of waste from the production process (e.g. solvent) is significantly reduced. The product is provided in high yield and purity (minimal amount of by-products and impurities). Compared to existing preparation methods, the method according to the invention has the advantage of low corrosiveness and high yield and high selectivity.