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公开(公告)号：US09434731B2
公开(公告)日：2016-09-06
申请号：US13905480
申请日：2013-05-30
发明人： Stephan Siegel , Andreas Wilmen , Susanne Röhrig , Niels Svenstrup , Mark Jean Gnoth , Stefan Heitmeier , Ulrich Rester , Adrian Tersteegen , Michael Gerisch
IPC分类号： A61K31/535 , C07D487/04 , C12N5/0789
CPC分类号： C07D487/04 , C12N5/0647
摘要： The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
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2.发明申请公开(公告)号：US20150166568A1
公开(公告)日：2015-06-18
申请号：US14336379
申请日：2014-07-21
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Joseph Pernerstofer
IPC分类号： C07D498/04 , C07D413/14 , C07D417/14 , C07D413/12 , C07D495/04
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
摘要翻译： 本发明涉及血液凝固领域。 描述了通式（I）的新型恶唑烷酮衍生物的制备及其作为用于预防和/或治疗病症的药物活性化合物的用途。
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公开(公告)号：US08846934B2
公开(公告)日：2014-09-30
申请号：US13770270
申请日：2013-02-19
发明人： Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Gnoth , Christoph Gerdes , Georges Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatman , Adrian Tersteegen
IPC分类号： C07D413/00 , A61K31/44 , C07D413/14
CPC分类号： C07D413/14
摘要： The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
摘要翻译： 本发明涉及新的取代的恶唑烷酮，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是血栓栓塞性疾病的药物的用途。
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4.发明授权公开(公告)号：US08822458B2
公开(公告)日：2014-09-02
申请号：US13961264
申请日：2013-08-07
发明人： Alexander Straub , Thomas Lampe , Jens Pohlmann , Susanne Röhrig , Elisabeth Perzborn , Karl-Heinz Schlemmer , Josef Pernerstofer
IPC分类号： A61K31/541 , C07D417/14
CPC分类号： C07D498/04 , A61K31/5377 , C07D333/38 , C07D409/12 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/14 , C07D495/04
摘要： The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
摘要翻译： 本发明涉及血液凝固领域。 描述了通式（I）的新型恶唑烷酮衍生物的制备及其作为用于预防和/或治疗病症的药物活性化合物的用途。
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