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公开(公告)号：US09505786B2
公开(公告)日：2016-11-29
申请号：US14738148
申请日：2015-06-12
发明人： Markus Follmann , Johannes-Peter Stasch , Gorden Redlich , Nils Griebenow , Dieter Lang , Frank Wunder , Walter Hübsch , Alexandros Vakalopoulos , Adrian Tersteegen
IPC分类号： C07D471/04 , A61K31/53 , A61P9/10 , A61P9/12 , A61P7/02 , C07D519/00 , A61K31/519 , A61K45/06
CPC分类号： C07D519/00 , A61K31/519 , A61K31/53 , A61K45/06 , C07D471/04
摘要： The present application relates to novel substituted fused pyrimidines and triazines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
摘要翻译： 本申请涉及新型取代的稠合嘧啶和三嗪，其制备方法，单独使用或组合用于治疗和/或预防疾病，以及其用于生产药物用于治疗和/或预防 疾病，特别是用于治疗和/或预防心血管疾病。
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公开(公告)号：US08846934B2
公开(公告)日：2014-09-30
申请号：US13770270
申请日：2013-02-19
发明人： Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Gnoth , Christoph Gerdes , Georges Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatman , Adrian Tersteegen
IPC分类号： C07D413/00 , A61K31/44 , C07D413/14
CPC分类号： C07D413/14
摘要： The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
摘要翻译： 本发明涉及新的取代的恶唑烷酮，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是血栓栓塞性疾病的药物的用途。
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公开(公告)号：US09434731B2
公开(公告)日：2016-09-06
申请号：US13905480
申请日：2013-05-30
发明人： Stephan Siegel , Andreas Wilmen , Susanne Röhrig , Niels Svenstrup , Mark Jean Gnoth , Stefan Heitmeier , Ulrich Rester , Adrian Tersteegen , Michael Gerisch
IPC分类号： A61K31/535 , C07D487/04 , C12N5/0789
CPC分类号： C07D487/04 , C12N5/0647
摘要： The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
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公开(公告)号：US09023849B2
公开(公告)日：2015-05-05
申请号：US13736692
申请日：2013-01-08
发明人： Markus Follmann , Johannes-Peter Stasch , Gorden Redlich , Nils Griebenow , Dieter Lang , Frank Wunder , Holger Paulsen , Walter Hübsch , Alexandros Vakalopoulos , Adrian Tersteegen
IPC分类号： A61K31/5365 , C07D253/00 , C07D487/04 , C07D519/00 , A61K31/519 , A61K31/53 , A61K45/06
CPC分类号： C07D487/04 , A61K31/519 , A61K31/53 , A61K45/06 , C07D519/00 , A61K2300/00
摘要： The present application relates to novel substituted fused imidazoles and pyrazoles, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases and to the use thereof producing medicaments for the treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
摘要翻译： 本申请涉及新颖的取代的稠合咪唑和吡唑，其制备方法，单独或组合用于治疗和/或预防疾病及其用于治疗和/或预防的药物的用途 的疾病，特别是用于治疗和/或预防心血管疾病。
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