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公开(公告)号：US20040180439A1
公开(公告)日：2004-09-16
申请号：US10759841
申请日：2004-01-15
IPC分类号： C12N015/74 , C07H021/04 , C12N015/85
CPC分类号： C12N15/85 , C12N9/0071 , C12N9/1051 , C12N9/127 , C12N9/503 , C12N15/113 , C12N15/63 , C12N15/69 , C12N15/8216 , C12N15/8218 , C12N15/8283 , C12N2800/108 , C12N2830/00 , C12N2830/002 , C12N2830/15 , C12N2830/38 , C12N2830/42 , C12N2830/55 , C12N2830/60 , C12N2840/102 , C12N2840/20
摘要： The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto.
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公开(公告)号：US20040266005A1
公开(公告)日：2004-12-30
申请号：US10821726
申请日：2004-04-08
IPC分类号： C12N015/85 , C07H021/04
CPC分类号： C12N15/85 , C12N9/0071 , C12N9/1051 , C12N9/127 , C12N9/503 , C12N15/113 , C12N15/63 , C12N15/69 , C12N15/8216 , C12N15/8218 , C12N15/8283 , C12N2800/108 , C12N2830/00 , C12N2830/002 , C12N2830/15 , C12N2830/38 , C12N2830/42 , C12N2830/55 , C12N2830/60 , C12N2840/102 , C12N2840/20
摘要： The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto.
摘要翻译： 本发明一般涉及用于修饰转基因生物体，特别是转基因动物或植物的细胞，组织或器官中的内源基因表达的合成基因。 更具体地说，本发明提供了新的合成基因和遗传构建体，其能够在引入生物体时抑制延迟或以其他方式降低生物体中的内源基因或靶基因的表达。
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